Blood test may pinpoint cause of stunted fetal growth
NCT ID NCT05151289
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This study is testing whether a simple blood test can help doctors tell apart two main causes of intrauterine growth restriction (IUGR) — a condition where a baby grows slower than expected in the womb. The test measures the ratio of two proteins, sFlt-1 and PlGF, which are linked to blood vessel problems in the placenta. Researchers will compare the test results with placental tissue analysis after birth to see if the test can accurately identify vascular causes. The study involves 167 pregnant women with a diagnosis of IUGR, and the findings could lead to a non-invasive way to guide pregnancy management.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Blood test measuring the sFlt-1/PlGF ratio
- What this could lead to
- If this blood test works, it could help doctors identify the cause of fetal growth restriction without invasive procedures, leading to better monitoring and care for at-risk pregnancies.
- What could go wrong
- This is a diagnostic study, not a treatment trial. The test may not be accurate enough to replace current methods, and results may vary across different populations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Louis Mourier
Colombes, 92700, France
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