Which radiotherapy technique offers best value for pelvic cancers?

NCT ID NCT01325961

Completed Disease control Sponsor: Institut Cancerologie de l'Ouest Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This trial compares three modern radiotherapy techniques—helical tomotherapy and two types of dynamic arc therapy (RapidArc and VMAT)—for treating prostate, cervical, and anal canal cancers that require pelvic lymph node irradiation. The goal is to determine which method is most cost-effective while maintaining treatment quality. The study includes 215 adults with locally advanced cancers who need radiation to the pelvic lymph nodes, often alongside chemotherapy or hormone therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy (IMRT via helical tomotherapy or dynamic arc therapy)
What this could lead to: If successful, this could identify the most cost-effective radiotherapy technique for treating pelvic cancers, potentially improving access and reducing healthcare costs.
What could go wrong: This is a cost-comparison study, not a test of new treatments. It may not show differences in cancer outcomes or side effects between the techniques.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anal canal cancer cervical cancer cervical carcinoma prostate cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANAL CANAL CANCERS CERVIX CANCER PROSTATE CANCER

Contacts and locations

Locations

Assistance publique des Hôpitaux de Marseille

Marseille, 13385, France
Centre Alexis Vautrin

Nancy, 54500, France
Centre Léon Bérard

Lyon, 69373, France
Centre Paul Strauss

Strasbourg, 67065, France
Centre Val d'Aurelle

Montpellier, 34298, France
Groupe Oncorad

Montauban, 82000, France
Groupe Oncorad

Toulouse, 31300, France
Hôpital Clinique Claude Bernard

Metz, 57 070, France
Hôpital Européen Georges Pompidou

Paris, Paris, 75015, France
Institut Bergonié

Bordeaux, 33000, France
Institut Claudius Regaud

Toulouse, 31000, France
Institut Curie

Paris, 75013, France
Institut Paoli Calmette

Marseille, 13273, France
Institut Sainte Catherine

Avignon, 84000, France
Institut de cancérologie de l'ouest

Saint-Herblain, 44800, France

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