Could removing extra lymph nodes during prostate surgery stop cancer from coming back?
NCT ID NCT01407263
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This trial asks whether removing lymph nodes during prostate cancer surgery lowers the chance of the cancer returning. Men with clear scans before surgery are randomly assigned to have lymph nodes removed or not. The study also tests other surgical tweaks, like how the incision is closed and how long antibiotics are given. The goal is to see if these changes improve outcomes and reduce side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Lymph node dissection during radical prostatectomy, plus other surgical modifications (closure type, antibiotic duration, hemostatic agent)
- What this could lead to
- If removing lymph nodes helps, it could reduce the chance of prostate cancer returning after surgery.
- What could go wrong
- The trial is large but results are not yet known; removing lymph nodes may not improve outcomes and could cause extra side effects like swelling or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Cancer Center @ Nassau (Consent only)
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Cancer Center at Basking Ridge
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Westchester
Harrison, New York, 10604, United States
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