Could a workout plan shield the heart during prostate cancer therapy?

NCT ID NCT07768917

NEW Not yet recruiting Disease control Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial tests whether a supervised strength and conditioning program can protect the heart and reduce inflammation in men with prostate cancer who are receiving radiation and hormone therapy. Participants will follow a structured exercise routine, and researchers will measure heart function, fitness, blood markers, and quality of life. The goal is to see if exercise can offset some of the cardiovascular side effects of cancer treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: A supervised and structured strength and conditioning exercise program
What this could lead to: If effective, this exercise program could help protect heart health and improve quality of life in men undergoing hormone therapy and radiation for prostate cancer.
What could go wrong: This is a small early-stage trial, so results may not apply broadly. The exercise program may not produce significant changes in heart or inflammatory markers.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.