CERVIX CANCER

This study tests whether combining two drugs, lenvatinib and pembrolizumab, can slow tumor growth in people with cervical cancer that has spread or come back. About 30 adults with certain types of cervical cancer will receive the treatment. The goal is to see if the combination h…

This early-stage trial tests a new drug, ONM-501, injected directly into tumors, either alone or with another drug (cemiplimab), for people with advanced solid tumors or lymphomas that have not responded to other treatments. The study aims to find the safest dose and check for si…

This study tests whether a shorter, higher-dose radiation schedule (hypofractionated) is as safe and effective as the standard longer schedule for women with locally advanced cervical cancer. About 278 women in Uganda will receive either the shorter or standard radiation, plus ch…

This study tests a gel spacer placed between the cervix and rectum during radiation therapy for cervical cancer. The gel creates space to protect nearby organs like the bladder and rectum from radiation damage. Researchers want to see if this approach is safe and feasible in 14 p…

This study is checking how often women with cervical or endometrial cancer have long-term side effects in their bowels or bladder after receiving a modern type of radiation called IMRT. Researchers will look back at the records of 300 women treated at Tata Memorial Hospital betwe…

This study uses data from 1,800 past cervix cancer patients to train machine learning models. The goal is to create software that can automatically outline tumors, predict side effects, and identify high-risk patients who might need stronger treatment. No new treatments are given…

This study looks back at medical records of 350 people with cervical cancer that has come back or spread to only a few places. The goal is to see how well different treatments like radiation, surgery, or chemotherapy work. By understanding what helps these patients live longer, d…

This study tests whether daily CT scans can help doctors see and protect the ovaries during pelvic radiation in women under 50 with various cancers. The goal is to keep radiation doses to the ovaries low enough to avoid early menopause and infertility. Ten participants will recei…

This study compares two ways to offer cervical cancer screening to women living with HIV: standard clinic-based screening versus also providing HPV self-collection kits through community health workers. About 2,900 women will take part to see if the community approach increases s…