Could a pill keep endometrial cancer at bay? new study tests rucaparib

NCT ID NCT03617679

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether the drug rucaparib can help keep metastatic or recurrent endometrial cancer from growing. 79 women who had already received chemotherapy took either rucaparib or a placebo pill twice daily. The goal was to see if rucaparib could delay cancer progression and improve survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rucaparib (a PARP inhibitor drug taken as a pill)

What this could lead to

If successful, rucaparib could offer a new maintenance option to delay cancer progression in people with advanced endometrial cancer.

What could go wrong

This is a Phase 2 trial with only 79 participants, so results may not be definitive. Rucaparib can cause side effects like fatigue, nausea, and low blood counts.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial carcinoma endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Colorado Hospital

    Aurora, Colorado, 80045, United States