Could a targeted drug shrink recurrent endometrial tumors?
NCT ID NCT00087685
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This phase II trial tests whether the drug RAD001 can shrink or slow the growth of tumors in people with recurrent endometrial cancer. Participants take RAD001 daily by mouth. The study measures how many patients have their tumors shrink or stay stable, and also tracks side effects. It includes people who have had up to two prior chemotherapies for their recurrent disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- RAD001 (everolimus)
- What this could lead to
- If successful, this could offer a new treatment option for people with recurrent endometrial cancer who have limited chemotherapy choices.
- What could go wrong
- This is an early-phase trial with only 35 participants, so results may not apply broadly. The drug may cause side effects and might not shrink tumors in all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a common Weight-Loss drug help hormone therapy work better for young women with endometrial cancer?
- New biologic drug DBC-664 takes aim at Hard-to-Treat cancers
- New imaging tool could help surgeons detect hidden cancer cells during surgery
- Could a simple diet replace an enema before endometrial cancer surgery?
- Proton beam therapy plus chemo aims to improve Post-Surgery treatment for advanced endometrial cancer