HPV vaccine during cervical surgery may cut infection risk

NCT ID NCT03979014

First seen Feb 01, 2026 · Last updated May 31, 2026 · Updated 15 times

Summary

This study tested whether giving the Gardasil 9 HPV vaccine at the same time as surgery to remove abnormal cervical cells could lower the chance of future HPV infections and prevent the return of high-grade cervical changes. About 1,100 women aged 18–55 took part. The goal was to see if the vaccine plus surgery works better than surgery alone.

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Contacts and locations

Locations

  • Frölunda Specialist Hospital Gynecology Clinic

    Västra Frölunda, 421 37, Sweden

  • Guy's and St Thomas' NHS Foundation Trust

    London, England, SE1 9RT, United Kingdom

  • Helsinki University Hospital

    Helsinki, 00280, Finland

  • Nottingham University Hospitals NHS Trust

    Nottingham, England, NG5 1PB, United Kingdom

  • Regionhälsan Masthugget Clinic of Obstetrics and Gynecology

    Gothenburg, 413 27, Sweden

  • Royal Preston Hospital - Lancashire Teaching Hospitals NHS Trust

    Fulwood, Preston, PR2 9HT, United Kingdom

  • Sahlgrenska University Hospital

    Gothenburg, 413 45, Sweden

  • St James's University Hospital, Leeds

    Leeds, England, LS9 7TF, United Kingdom

  • St Mary's Hospital - Imperial College Healthcare NHS Trust

    London, SW7 2BT, United Kingdom

  • St. Mary's Hospital - Manchester University NHS Foundation Trust

    Manchester, England, M13 9WL, United Kingdom

  • Tampere University Hospital

    Tampere, 33520, Finland

  • West Middlesex University Hospital

    London, England, TW7 6AF, United Kingdom

  • Whittington Health NHS Trust

    Middlesex, England, N19 5NF, United Kingdom

Conditions

Explore the condition pages connected to this study.