Could a blast of argon plasma wipe out cervical precancer without surgery?
NCT ID NCT07730645
First seen Jul 28, 2026 · Last updated Aug 04, 2026 · Updated 3 times
Summary
This trial tests whether a single, outpatient treatment using low-thermal argon plasma can clear grade 2 cervical intraepithelial neoplasia (CIN2), a precancerous condition. Participants receive either the plasma treatment, a sham procedure, or standard active surveillance. The main goal is to see if the plasma treatment leads to complete healing of the abnormal tissue after six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- low-thermal argon plasma devitalization (LtAPD) applied via a device
- What this could lead to
- If effective, this one-time outpatient procedure could offer a non-surgical way to clear high-grade cervical precancer, potentially reducing the need for more invasive treatments.
- What could go wrong
- This is a mid-sized trial comparing the plasma treatment to a sham procedure and active surveillance. The effect may be modest, and long-term outcomes beyond 6 months are not yet known.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital Tuebingen, Department of Women's Health
Tübingen, Baden-Wurttemberg, 72076, Germany
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