New radiation technique may spare bowel in cervical cancer treatment

NCT ID NCT01279135

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 3 trial tested whether a newer, more precise type of radiation (image-guided intensity modulated radiotherapy) could reduce long-term bowel problems compared to standard radiation in 300 women who had surgery for cervical cancer. The study focused on lowering severe bowel side effects that can occur months or years after treatment. Results could help doctors choose the best radiation approach to improve quality of life.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Radiation therapy (image-guided intensity modulated radiotherapy vs conventional radiotherapy)
What this could lead to
If successful, this could establish a new standard of care that reduces long-term bowel damage for women receiving radiation after cervical cancer surgery.
What could go wrong
This trial is completed, but results may not apply to all patients or settings. The benefit may be modest, and some side effects may still occur.

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Conditions

The condition(s) this trial relates to.

cervical cancer cervical carcinoma Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre

    Navi Mumbai, Maharashtra, 410210, India

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