Supplements before fibroid surgery show promise in small study

NCT ID NCT06768086

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested whether taking a combination of EGCG (from green tea), vitamin D, and D-chiro-inositol for three months before hysteroscopic myomectomy improves surgical outcomes. 90 women with uterine fibroids were divided into two groups: one received the supplements before surgery, the other did not. Researchers compared surgery time, fluid use, and how completely fibroids were removed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Epigallocatechin gallate (EGCG), vitamin D, and D-chiro-inositol

What this could lead to

If it works, this could make hysteroscopic myomectomy faster and more complete for women with uterine fibroids.

What could go wrong

This is a small pilot study (90 participants) with no blinding or placebo, so results may not be reliable or generalizable. The supplements may not meaningfully improve surgery outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

leiomyoma myofibroma Patient Compliance uterine corpus leiomyoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ospedale Veris delli Ponti

    Scorrano, Lecce, 73020, Italy