Could a daily aspirin protect diabetic Moms-to-Be?

NCT ID NCT03574909

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether taking low-dose aspirin (150 mg) daily, starting in the first trimester, could reduce pregnancy complications in women with type 1 or type 2 diabetes. The trial included 137 women and looked at outcomes like preeclampsia, early preterm birth, low birth weight, and infant death. The goal was to see if this simple, cheap medicine could improve safety for both mother and baby.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
low-dose aspirin (150 mg prolonged-release capsule)
What this could lead to
If it works, this could point toward a simple, low-cost way to lower the risk of serious pregnancy complications like preeclampsia and preterm birth in women with diabetes.
What could go wrong
This trial is relatively small (137 participants) and completed, but results may not apply to all women with diabetes. Aspirin also carries a small risk of bleeding or allergic reactions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rotunda Hospital

    Dublin, Ireland

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