Gestational diabetes

This study will give 800 pregnant women biweekly food kits with fruits, vegetables, and other healthy foods to see if it improves their diet and pregnancy outcomes. Participants will be followed from early pregnancy through birth. The goal is to learn whether providing healthy fo…

This study follows 630 people with type 1 diabetes in Japan who are already prescribed Awiqli, a once-weekly injection. Researchers will track side effects and blood sugar control over one year to see how the drug works in everyday life. The goal is to manage diabetes, not cure i…

This study tests whether a continuous glucose monitor (CGM) paired with a coaching app helps pregnant women with type 2 diabetes achieve better blood sugar control compared to standard care. Participants use a Dexcom G7 CGM sensor and receive guidance through a mobile app and car…

This study tests whether providing money specifically for healthy foods helps pregnant women avoid gaining too much weight. About 1,440 women will either get standard nutrition advice or that plus up to $3,000 for healthy groceries. Researchers will compare weight gain between th…

This study compares two blood sugar targets for overweight or obese women with gestational diabetes. One group aims for stricter goals (fasting under 90 mg/dL, after meals under 120 mg/dL), while the other follows standard targets (fasting under 95 mg/dL, after meals under 140 mg…

This study compares two treatments for gestational diabetes: oral metformin pills and injectable insulin. Researchers want to see if metformin is as good as insulin at preventing problems for mothers and babies, like high birth weight or low blood sugar. About 1,500 pregnant wome…

This study tests whether wearing a continuous glucose monitor (CGM) helps pregnant women with gestational diabetes control their blood sugar and improve outcomes for both mother and baby. Researchers will also examine how socioeconomic status, diet, and culture affect results. Th…

This study tests if leg exercise (like pedaling) is better than arm exercise for controlling blood sugar, weight, and stress in pregnant women with gestational diabetes. 108 women in their second trimester will exercise three times a week for eight weeks. The goal is to find a sa…

This study tests whether a continuous glucose monitor (CGM) can improve pregnancy outcomes for women with gestational diabetes compared to standard finger-prick testing. About 386 women from Belgium and Australia will be randomly assigned to use either a CGM or a regular glucomet…

This study tests whether a continuous glucose monitor (CGM) helps control blood sugar better than standard finger-stick checks for people with diabetes who are recovering at home through Mayo Clinic's Advanced Care at Home program. About 100 participants will use the Dexcom G6 PR…

This study tests a bone marrow transplant from a family donor for children under 21 with severe non-cancer blood disorders like sickle cell disease, bone marrow failure, or immune problems. The goal is to see if the transplant can replace the diseased cells with healthy donor cel…

This study looks at whether automated insulin delivery (AID) systems can safely manage blood sugar during labor and delivery for pregnant people with type 1 diabetes. About 150 participants will be randomly assigned to use their usual AID system or standard intravenous insulin. T…

This study tests a new way of caring for new mothers and their babies together, called MOMI PODS. It focuses on moms who had heart or mental health problems during pregnancy. The goal is to see if this coordinated care model improves health and reduces risks like postpartum depre…

This study compares taking insulin glargine once versus twice daily in pregnant women with type 2 diabetes who need insulin. Two hundred participants will be randomly assigned to one of the two dosing schedules, and their blood sugar levels will be tracked continuously. The goal …

This study tests whether community health workers can help women in urban slums of India get screened for type 2 diabetes after having gestational diabetes. 330 women will either receive home-based testing or a referral to a clinic, plus diabetes education. A smaller part of the …

This study tests a structured behavioral program called the BMW Toolkit for pregnant women with both gestational diabetes and pregnancy-induced hypertension. The toolkit includes diet, exercise, sleep, and self-care guidance delivered over 7-8 sessions. Researchers will compare b…

This study is testing a new continuous glucose monitoring system called ROME GS in 60 adults with type 1 or type 2 diabetes. The goal is to see if it measures blood sugar accurately and is safe to use. Participants will wear the sensor and have their glucose levels checked agains…

This study is testing a new glucose monitoring system called Eversense Gemini, which includes a flash glucose measurement feature. The goal is to see how accurate and safe it is for adults with type 1 or type 2 diabetes. About 80 participants will wear the device and have their g…

This study tests whether a single daily dose of long-acting insulin can control blood sugar as well as the usual regimen of long-acting insulin plus mealtime insulin in pregnant women with diabetes. About 176 participants will be randomly assigned to one of the two approaches and…

This study tests whether giving pasteurized donor human milk to full-term babies of mothers with diabetes during the first five days of life can reduce the number of infants admitted to the neonatal unit for low blood sugar. About 1,444 mothers and their newborns will be randomly…

This study tests whether a lifestyle program delivered through a mobile app, combined with a continuous glucose monitor (Abbott FreeStyle Libre 2), can improve blood sugar control and reduce cardiometabolic risk in 120 pregnant women diagnosed with gestational diabetes. Participa…

This study tests whether a more intensive approach—combining a structured low-calorie diet, moderate exercise, and frequent monitoring—works better than standard counseling for managing gestational diabetes. Sixty pregnant women will be randomly assigned to one of two groups. The…

This study tests whether a 6-month lifestyle program (diet, exercise, coaching) or the drug metformin is better for weight loss in mothers who recently had gestational diabetes. Sixty women who gave birth in the last year will join. Participants track their activity and weight, a…

This study tests whether wearing a continuous glucose monitor (CGM) early in pregnancy can quickly detect and manage high blood sugar in 6,000 pregnant women. The goal is to reduce serious problems for the baby (like being too large, birth injuries, or NICU stays) and for the mot…

This pilot study at Johns Hopkins University will enroll 40 Black women who recently had gestational diabetes and are overweight. Half will receive prepared low-carb, low-fat meals plus nutrition counseling, lactation support, and culturally tailored food bundles; the other half …

This study looks at whether a moderate carbohydrate diet (up to 120g per day) can help pregnant women with diabetes who need insulin achieve better blood sugar control compared to the standard high-carb diet. The trial will include 120 pregnant women and track their glucose level…

This study tests whether wearing a continuous glucose monitor that shows real-time blood sugar levels on a smartphone app, plus joining a group chat with other pregnant women, helps keep glucose levels healthy during pregnancy. About 70 pregnant women at risk for gestational diab…

This study tests whether screening for gestational diabetes in the first trimester (instead of the usual third trimester) can detect the condition earlier in high-risk pregnancies. Researchers will use a combination of risk factors and blood markers to predict GDM. The goal is to…

This pilot study will enroll 150 pregnant individuals to see if a continuous glucose monitor (CGM) can accurately diagnose gestational diabetes. Participants will wear a small sensor on their arm that measures blood sugar continuously. The results will be compared to the standard…

This study is testing two new ways to predict gestational diabetes and large babies (macrosomia) in pregnant women. Researchers will measure skin autofluorescence and glycated albumin in 800 pregnant women and compare them to the standard HbA1c test. The goal is to see if these m…

This study looks at whether doing a diabetes test right after giving birth (instead of waiting 4-12 weeks) helps more women get screened for type 2 diabetes after having gestational diabetes. It also asks women about their views on heart-health programs after pregnancy. About 104…

This study compares a glucose tolerance test given right after childbirth to the standard test given 6 weeks later in women with gestational diabetes. Researchers want to see if the early test is accurate and if it helps more women get tested. About 300 women will participate.

This pilot study is testing whether eating fermented poi every day for four weeks can improve the gut health of pregnant women and lower their risk of developing gestational diabetes. Fifty pregnant women between 10 and 24 weeks will eat one pound of poi daily and receive nutriti…

This study tests whether screening women for type 2 diabetes while they are still in the hospital after giving birth can help catch the disease early and prevent it. About 116 women who had gestational diabetes will be randomly assigned to either early testing or usual care. The …

This study tests whether the drug semaglutide can prevent type 2 diabetes in women who had gestational diabetes and now have high blood sugar after pregnancy. About 252 women will receive either semaglutide or a placebo for several months. The goal is to see if the drug lowers th…

This study aims to develop a better system to support breastfeeding for women who had gestational diabetes, with the goal of preventing type 2 diabetes later. Researchers will work with patients, healthcare providers, and hospital leaders to design a practical strategy. Only 10 p…

This study tests whether extra lifestyle coaching plus medically tailored meals can help prevent type 2 diabetes in mothers who had gestational diabetes. Nearly 1,000 pregnant or recently postpartum women from home visiting programs will be randomly assigned to receive either enh…

This study tests an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) designed for young women aged 18-39 with overweight or obesity who may become pregnant within two years. Participants will either join online group classes for 12 months or receive sta…

This study tests whether limiting eating to a 10-hour window each day can lower the chance of developing gestational diabetes in pregnant women at high risk. Researchers will compare this approach to usual eating habits over 3 months in 240 women. The goal is to see if this simpl…

This study tests whether taking vitamin D and prebiotics (inulin) during early pregnancy can help control blood sugar in women at high risk for gestational diabetes. 500 pregnant women will receive supplements or placebos from 6-15 weeks of pregnancy. The goal is to see if these …

This study will test whether giving women with gestational diabetes a home ultrasound device, guided remotely by a doctor, improves their satisfaction and health outcomes compared to standard care. About 90 participants will use the device for fetal checks from home. The goal is …

This pilot study is testing a smartphone app called MyGlucoCare that provides personalized education, clinician support, and a peer group for women with gestational diabetes. About 30 pregnant women will use the app for 8 to 12 weeks. Researchers want to see if the app is practic…

This study tests whether natural cervical ripening methods can help labor start on its own in pregnant women with diet-controlled gestational diabetes. About 74 participants will try these methods starting at 37 weeks to see if they can avoid a medically induced labor. The goal i…

This pilot study is testing how exenatide, a drug already used for type 2 diabetes, works in pregnant women with gestational diabetes. Researchers will measure how the body processes the drug and how well it controls blood sugar after a meal. The study involves 13 pregnant women …

This study tests whether eating protein and fat (scrambled eggs) before carbohydrates (toast) can reduce blood sugar spikes in women with gestational diabetes. Thirty-five pregnant women will eat the same breakfast in two different orders on separate days, acting as their own con…

This study follows 600 Indigenous families in Manitoba to understand how maternal health, genetics, and early-life environment contribute to obesity and type 2 diabetes in children. Pregnant women with type 2 diabetes, gestational diabetes, or no diabetes are enrolled, and their …

This study looks at children with suspected or confirmed genetic and metabolic disorders to find new disease-causing gene mutations. Researchers will analyze blood samples for DNA and metabolites, and in some cases take a small skin sample. The goal is to better understand these …

This study at the National Institutes of Health is looking at 1,000 adults with known or suspected hormone gland (endocrine) disorders. The goal is to better understand these conditions and help train doctors. Participants may receive tests, treatments, or surgery as part of thei…

This study enrolls up to 15,000 children with known or suspected endocrine or metabolic disorders, along with their family members. Researchers will collect medical records, blood, saliva, and other samples to identify genetic changes linked to these conditions. The goal is to be…

This study is creating a large collection of blood, urine, stool, and heart tissue samples from 10,000 people with and without heart or metabolic conditions. The goal is to store these samples along with medical information to speed up future research into what causes these disea…

This study tests a program called SPARK-CGM that helps primary care clinics prescribe continuous glucose monitors (CGM) to people with diabetes. CGM devices track blood sugar in real-time, but they are underused in primary care. The program provides training, workflow support, an…

This study aims to collect medical data and biological samples (blood, urine, stool, and tissue) from up to 4,000 adults with known or suspected gastrointestinal diseases. Participants receive standard medical care at the NIH, and any extra samples or leftover tissue from procedu…

This study is collecting health data from 1,500 adults with diabetes in Switzerland to see how well current treatments work in everyday life. Researchers will track complications, quality of life, and survival over time. The goal is to find out what's working and what needs impro…

This study reviews medical records of 500 adults treated for benign or malignant pancreatic diseases since 2005. The goal is to understand how well different treatments worked over time. No new treatments are given—just careful analysis of past cases.

This study looks at whether drinking 200 ml of water two hours before a planned C-section changes stomach volume differently in pregnant women with diabetes compared to those without. Researchers will use ultrasound to measure stomach contents before and after drinking. The goal …

This study tests a new communication tool called 'Let's Get REAL' that helps children and teens (ages 8-17) and their families talk together about stem cell transplant or cellular therapy decisions. The goal is to see if the tool is easy to use and helpful for families. About 60 …

This study looks at whether a genetic risk score can predict which people with newly diagnosed diabetes will eventually need insulin. Researchers will follow about 3,000 patients aged 14 to 50 for up to 3 years, tracking their C-peptide levels (a marker of insulin production) and…

This study follows 140 pregnant women who conceived while still breastfeeding. Researchers want to see if breastfeeding lowers the chance of developing gestational diabetes in the new pregnancy. They will track blood sugar levels and baby growth to find out.

This study looks at whether treating gestational diabetes early (before 24 weeks) is better than waiting until the standard 24-28 week screening. About 2,010 pregnant women with mild early high blood sugar will be randomly assigned to either start intensive treatment right away o…

This study is checking how accurate the Dexcom G7 continuous glucose monitor is for patients in the intensive care unit after major abdominal surgery or organ transplant. Researchers will place two sensors on each patient—one that is calibrated and used to guide insulin dosing, a…

This study is collecting blood samples from 1,160 people with and without type 1 diabetes to analyze the immune cells that mistakenly attack the pancreas. The goal is to better understand how these cells work, which could lead to improved treatments or prevention strategies in th…

This study enrolls adults with known or suspected endocrine (hormone gland) disorders, such as diabetes or thyroid disease, to help researchers learn more about these conditions. Participants will undergo medical exams, blood and imaging tests, and possibly genetic testing. The m…

This study looks at how growth hormone affects beta-cells, which make insulin to control blood sugar, in women who had gestational diabetes. Researchers will compare women with and without a history of gestational diabetes to better understand risk factors. The goal is to learn m…

This study looks at how a pregnant person's metabolism—specifically insulin resistance and fat burning—may be linked to placenta health and pregnancy complications like preeclampsia and gestational diabetes. Researchers will follow 50 pregnant women at high or moderate risk for p…

This study tests whether sending automatic WhatsApp reminders helps more women with gestational diabetes attend their postpartum glucose test. It also compares a newer one-hour blood sugar measurement to the standard two-hour test to see which catches prediabetes and diabetes ear…

This study is a large registry that will follow 20,000 people with type 1 diabetes across China. It aims to track changes in blood sugar, kidney function, heart health, and emotional well-being over many years. The goal is to better understand how the disease progresses and impro…

This study follows 800 pregnant women—some healthy, some with obesity or diabetes—to understand how these conditions affect both mother and baby during pregnancy and after birth. Researchers will track body composition, blood sugar, blood pressure, and other health markers throug…

This study follows 400 pregnant women diagnosed with gestational diabetes to understand how it affects their health and their baby's health. Researchers will track things like blood sugar, blood pressure, and body fat during pregnancy and after birth. The goal is to learn more ab…

This study follows 462 women pregnant after egg donation or standard IVF to learn why pre-eclampsia is more common in egg donation pregnancies. Participants give blood samples and have regular check-ups throughout pregnancy. The goal is to find early warning signs and improve car…

This study looks at whether routine blood sugar tests (like fasting glucose and HbA1c) can predict gestational diabetes in pregnant women who have had bariatric surgery and cannot tolerate the standard sugary drink test. Researchers will follow 84 women throughout pregnancy to se…

This study looks at how three common blood pressure medications (ephedrine, phenylepinephrine, and norepinephrine) affect the ability of the uterus to contract after a C-section in women with type 2 or gestational diabetes. Researchers will take small tissue samples from the uter…

This study looks at how the metabolism of both parents during pregnancy may change the baby's epigenetics—chemical marks on DNA—in gestational diabetes. Researchers will test 80 pregnant women and their partners, analyzing blood and fetal cell-free DNA. The goal is to better unde…

This study is testing a tool called B-COMPASS that uses a 22-question survey to predict whether people will follow their prescribed treatments. Researchers will enroll 3100 adults with cardiovascular, endocrine, immune, nerve, cancer, or rare diseases across Europe. The goal is t…

This study follows 600 pregnant women with gestational diabetes to see how depression and diabetes affect each other during pregnancy and after birth. Some participants will receive short health education videos about diet, exercise, and support. The goal is to understand the con…

This study looks at how tiny particles released by the placenta, called extracellular vesicles, affect pregnancy complications like pre-eclampsia and gestational diabetes. Researchers will collect samples from 360 pregnant and non-pregnant women to understand these particles bett…

This pilot study is testing whether wearing a continuous glucose monitor (CGM) for just 24 hours after giving birth can help predict a woman's long-term risk of developing type 2 diabetes. The study involves 50 women who had gestational diabetes and will wear the CGM immediately …

This study looks at whether avoiding non-nutritive sweeteners (like those in diet sodas) during pregnancy and breastfeeding can lower babies' risk of obesity and improve mothers' blood sugar control. About 324 pregnant women who regularly consume these sweeteners will be split in…

This study uses MRI scans to look for brain differences in people with metabolic diseases compared to healthy volunteers. Researchers will track changes over time and link them to body fat and other health measures. About 126 adults will take part at Ulm University Hospital. No d…

This study looks at whether a continuous glucose monitor (CGM) — a small sensor worn under the skin — is an acceptable and useful tool for checking diabetes risk in women who recently had gestational diabetes. Twenty women will wear the CGM for 10 days at 6-8 weeks after giving b…

This observational study follows 100 pregnant women with gestational diabetes to see how sleep quality, anxiety, eating habits, and lifestyle relate to blood sugar control and birth outcomes. Participants complete questionnaires and undergo glucose monitoring either at home or du…

This study tracks 1,000 patients undergoing major liver, pancreas, or bile duct surgery to see if the time it takes for their albumin levels to return to normal can predict complications and length of hospital stay. Albumin is a protein that drops after surgery due to inflammatio…

This study uses a special MRI technique to compare blood flow and oxygen levels in the placentas of pregnant women with diabetes versus healthy pregnant women. Researchers will enroll 40 participants to see if diabetic placentas have lower blood flow. The goal is to better unders…

This study looks at how having gestational diabetes during pregnancy might affect blood flow and blood vessel function in the brain after childbirth. Researchers will use ultrasound to measure brain blood flow in women who had gestational diabetes and compare them to women with h…

This study looks at why women who had gestational diabetes (diabetes during pregnancy) often have higher heart disease risk years later. Researchers will test how a natural chemical called endothelin-1 affects small blood vessels in 40 women who had a baby within the last 5 years…

This study will follow 1000 pregnant women to find what raises the risk of gestational diabetes and create a tool to predict it early. Then, some women will try a personalized health plan (GLOW plan) to see if it improves blood sugar control. The goal is to reduce short- and long…

This observational study at Turku University Hospital will use ultrasound radiomics to compare fetal liver texture between 60 pregnant women with type 1 diabetes and healthy controls. The goal is to see if this noninvasive method can detect signs of fetal hyperinsulinemia (high i…

This study follows 2,800 pregnant women and their children in Weifang, China, from early pregnancy until the child turns 18. Researchers collect data on diet, lifestyle, and environment, along with blood, urine, and other samples. The goal is to understand how factors before and …

This study looks at whether women with gestational diabetes (GDM) experience muscle loss, known as sarcopenia, and how this might affect pregnancy outcomes and thinking skills. Researchers will test 200 pregnant women using muscle strength and function tests, along with standard …

This study follows 100 pregnant women with gestational diabetes to understand how their daily blood sugar patterns relate to their baby's growth. Participants wear a continuous glucose monitor for 14 days and have routine checkups. The goal is to learn which blood sugar patterns …

This pilot study is testing whether it's practical to run a larger trial that compares inducing labor at 38 weeks versus waiting for natural labor in people with gestational diabetes. About 260 participants will be randomly assigned to either early induction or expectant manageme…

The SMILE study is tracking 10,000 adults aged 18 and older to see how sarcopenia (age-related muscle loss) and metabolic diseases like diabetes influence overall health and lifespan. Researchers will collect data from medical records, tests, and surveys over time. This is an obs…

This study looks at whether continuous glucose monitors (CGMs) worn during late pregnancy and for two weeks after birth can predict which women with gestational diabetes will have abnormal blood sugar after delivery. Currently, only a small percentage of women complete the standa…

This study looks at how pregnant women at risk for preeclampsia process aspirin and how that relates to signs of metabolic problems. Researchers will measure aspirin byproducts in blood and urine, along with other health markers, in 50 women. The goal is to better understand why …

This study will follow 4,000 pregnant women with high blood sugar (gestational diabetes or pre-existing diabetes) to create better standards for diagnosis, treatment, and follow-up. Researchers will track health problems in mothers and babies, like preeclampsia or preterm birth, …

This study follows 100 children under 18 who are already on a ketogenic diet for conditions like drug-resistant epilepsy, autism, chronic migraine, or brain tumors. Researchers want to see if the diet supports healthy growth, improves symptoms, and boosts quality of life. The die…