Could a pregnancy complication leave lasting damage to blood vessels? new study investigates
NCT ID NCT06547619
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at why women who had gestational diabetes (diabetes during pregnancy) often have higher heart disease risk years later. Researchers will test how a natural chemical called endothelin-1 affects small blood vessels in 40 women who had a baby within the last 5 years. They will also see if physical activity or sitting too much plays a role. The goal is to understand the problem better, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
insulin aspart
What this could lead to
If successful, this could reveal why women with prior gestational diabetes have higher heart disease risk, pointing toward future prevention strategies.
What could go wrong
This is a very small, early-phase study (40 participants) that measures short-term responses in skin blood vessels, not long-term outcomes. Results may not apply to all women or lead directly to treatments.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••