Five minutes a day: breathing training may tame pregnancy blood pressure

NCT ID NCT07687745

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study tests whether a simple breathing exercise, called Inspiratory Muscle Strength Training (IMST), can safely lower blood pressure in pregnant women during their third trimester. Participants do 5 to 8 minutes of breathing against light or moderate resistance each day for six weeks at home. The goal is to see if this easy, drug-free approach can help prevent or reduce high blood pressure disorders in pregnancy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Inspiratory Muscle Strength Training (IMST)
What this could lead to
If effective, this simple home-based breathing exercise could offer a safe, drug-free way to help manage blood pressure during pregnancy.
What could go wrong
This is an early-phase trial with only 80 participants, so results may not apply broadly. The breathing exercise may not lower blood pressure significantly, and some women may find it uncomfortable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female sex * Pregnant (32 to 34 weeks of gestation, confirmed by ultrasound, at the time of first training session, eligible patients may consent/enrolled earlier in pregnancy) * Singleton pregnancy * Age 18 to 55 * Able to read English and provide consent * Possess smartphone for syncing the AiroFit and Omron devices using Bluetooth and completing online surveys * Smartphone updated to iOS 12+ or Android 11+ * No contraindication for moderate exercise at time of enrollment * Not planning delivery for at least one month at time of enrollment (\< 38 weeks of gestation) * Willing to adhere to AiroFit device use throughout study period * Must already be scheduled, or in the process of scheduling, for weekly NST appointments by 32 to 34 weeks gestational age (per provider order / due to obstetric indication) Lower-Risk Pregnancy Cohort Inclusion Criteria: * No history or evidence of hypertensive disorders of pregnancy * May be undergoing antenatal testing for: * Conception via in vitro fertilization, BMI ≥ 35, an advanced maternal age (age \>/=35), or other condition not listed in exclusion criteria or 'higher risk for HDP group' but is recommended for antenatal testing. Higher-Risk Pregnancy Cohort Inclusion Criteria: * Conditions associated with higher risk of developing HDP, including: * Gestational diabetes mellitus, chronic hypertension, gestational hypertension, or a history of preeclampsia in a previous pregnancy Exclusion Criteria: * Younger than 18 or older than 55 years of age * Multiple gestation (twin or higher-order pregnancy) * Fetal chromosomal abnormalities or major anatomical anomalies * Planning to deliver earlier than 38 weeks or within 4 weeks of study enrollment * Any contraindication for moderate exercise (e.g., cardiomyopathy, congenital cardiac conditions) * Deep vein thrombosis * Complications in current pregnancy including intrauterine growth restriction (IUGR), oligohydramnios, preeclampsia, or severe-range blood pressures (\>/=160/110 or \<100/60) * Active vaginal bleeding, or history of coagulopathy * Placenta previa or other placental abnormalities (including placental cyst or abruption) * Signs of labor * Current substance use disorder * History of neurological, respiratory, head/neck, or thoracic surgeries, or conditions such as collapsed lung or perforated eardrum * Individuals with any of the following: * Chronic obstructive pulmonary disorder (COPD) * Severe asthma * Severe ischemic heart disease * Left-sided heart failure * Chronic laryngitis, chronic bronchitis, emphysema, pneumonia * Latent or active tuberculosis * Chronic cough * Neurological problems (e.g. seizure disorder) * Severe scoliosis with no history of surgical correction or management. * Organ transplant * HIV or other immunocompromising conditions * Autoimmune disease with possible vascular complications (e.g. Lupus) * Significant respiratory compromise (e.g., severe dyspnea, O₂ saturation \<95%, uncontrolled asthma, history of pneumothorax)

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Blood pressure measurement in pregnancy are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Banner University Medical Center

    RECRUITING

    Tucson, Arizona, 85719, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.