University Of Arizona

This study is testing a 3-week diet and exercise program for American Indian adults with obesity-related cancers who are scheduled for surgery. The program includes eating walnuts, walking daily, and supervised exercise sessions to see if it's practical for patients and if it can…

This study is testing whether a smartphone app can help older adults who have mild memory problems remember to take their blood pressure medication. Researchers will enroll 100 adults aged 60 and over. Participants will use an app that provides reminders and educational informati…

This study is testing whether a personalized, flexible program to help adults extend their nightly sleep can improve their health and well-being. It's enrolling over 1,000 adults aged 18-60 who typically sleep 6 hours or less per night. Researchers will use participants' Fitbit d…

This study is testing whether it is safe to combine a new targeted drug called tarlatamab with standard radiation therapy. It is for adults with advanced cancers that have a specific protein called DLL3, including certain lung cancers, melanoma, and others. The main goal is to se…

This study is testing whether a program led by community health workers is practical and acceptable for helping Mexican-origin adults with fatty liver disease (MASLD) improve their heart health. The program aims to increase awareness of cardiovascular risks and promote healthy li…

This study is testing a new support program for people who have trouble taking their blood pressure medicine as prescribed. It pairs a pharmacist with a community health worker to help patients overcome personal and practical barriers to taking their medications. The goal is to s…

This study is testing whether a weekly infusion of a natural hormone called Allopregnanolone can help repair brain structure and slow memory loss in people with mild Alzheimer's disease. About 100 participants will receive either the treatment or a placebo for six months, with br…

This study is testing a combination of two chemotherapy drugs delivered directly into the bladder to treat non-invasive bladder cancer. The treatment aims to control the cancer and prevent it from returning, potentially helping patients avoid major surgery. Researchers want to se…

This study is testing if adding the drug tadalafil (Cialis) to standard chemotherapy before stomach cancer surgery is safe and helpful. Researchers want to see if this combination changes the environment around the tumor to make treatment more effective. About 10 patients with op…

This study is testing whether certain patients can safely go home the same day they have colon surgery, instead of staying in the hospital overnight. Researchers will follow 150 carefully selected, generally healthy adults who have robotic-assisted colon surgery. The main goal is…

This study is testing whether a special type of PET/CT scan using a tracer called 18F-fluciclovine can better identify and monitor brain metastases (cancer that has spread to the brain). Researchers want to see if this scan can more clearly show active cancer versus treatment sid…

This study tests whether a community-based telehealth program can help more people get screened for colon cancer. The program sends video text messages, mails home test kits, and provides patient navigation support to overcome barriers like misinformation and access issues. Resea…

This study compares two ways to use caffeine to stay alert when you're very sleep-deprived. Researchers want to see if a personalized smartphone app that recommends caffeine doses works better than standard advice. They will test 180 healthy young adults who will stay awake for o…

This study is testing a new program designed to help Hispanic adults with knee osteoarthritis become more active. Participants will be paired with a family member or close friend and will receive video sessions. The program includes education, strength exercises, and a plan to in…

This study is testing a new device designed to relieve the pain and numbness of carpal tunnel syndrome. The device is worn on the wrist at night and applies gentle, rhythmic pressure. Researchers are comparing this new device to a standard wrist brace to see which one better impr…

This study is testing whether a non-invasive magnetic brain stimulation technique can help people with insomnia sleep better. Researchers will recruit 144 adults with insomnia to receive either real or sham (fake) magnetic pulses to different parts of the brain over two to three …

This study is testing whether daily morning light exposure can help improve mood and reduce suicidal thoughts in military personnel. It will involve 480 service members wearing a special light headset for 30 minutes each morning for two weeks. Researchers will compare the effects…

This study aims to see if custom 3D-printed ear tips for hearing aids are as comfortable and sound as good as standard tips. Researchers will test 30 people with normal hearing to compare fit, comfort, and sound quality. They will also measure how long it takes and how much it co…

This study is testing a new, non-drug approach to manage chronic knee pain in older adults with Alzheimer's or related dementias. Over four weeks, 40 participants will try a home-based program that combines gentle brain stimulation (tDCS) with online seated yoga sessions, all sup…

This study is testing whether watching TV shows or movies in a small group, with guided discussions about emotions, can help improve mental well-being. About 70 adults receiving long-term mental health care will participate in six weekly 90-minute sessions. Researchers will compa…

This study is testing whether a simple, 10-day meditation program delivered through a smartphone app can help reduce anxiety and depression in career firefighters. Researchers will compare the meditation app to a health education app to see which is more effective at lowering psy…

This study aims to understand if omega-3 fatty acid supplements improve heart health differently for people based on their genetic background and ancestry. Researchers will give 200 healthy adults either omega-3 pills or a placebo for 12-week periods and measure changes in blood …

This study is collecting and storing tumor tissue, blood, and urine samples from cancer patients to create a resource for future research. It aims to help scientists better understand cancer by providing them with high-quality samples linked to patient health information. Partici…

This study aims to understand how major pancreas surgery affects patients' quality of life, symptoms, and financial well-being over two years. Researchers will follow 250 adults who choose to have this surgery for tumors, cysts, or pancreatitis. The goal is to gather detailed pat…

This study aims to understand why suicide risk appears higher during the late-night hours. Researchers will observe about 90 adults who have recently experienced suicidal thoughts, testing their mood and decision-making when awake between 2:00 and 4:00 AM. The goal is to learn if…