Heart clot showdown: could a simpler blood thinner replace warfarin?

NCT ID NCT07709780

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This trial tests whether apixaban, a newer blood thinner with fixed dosing, works as well as warfarin for dissolving dangerous blood clots in the heart's main pumping chamber. Adults with a confirmed left ventricular thrombus are randomly assigned to receive either apixaban or warfarin for at least three months. The main goal is to see if apixaban is no worse than warfarin at completely clearing the clot, as seen on heart MRI scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
apixaban and warfarin
What this could lead to
If apixaban works as well as warfarin, it could offer a simpler, safer treatment option for left ventricular thrombus without the need for frequent blood monitoring.
What could go wrong
This is a relatively small trial, and apixaban may not prove as effective as warfarin for dissolving the clot. Bleeding risks exist with both drugs.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Banner University Medical Center - Tucson

    RECRUITING

    Tucson, Arizona, 85724, United States

    Contact

    Contact

    Contact

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