New imaging sheds light on hidden heart clots after attack
NCT ID NCT04829825
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 100 people who recently had a major heart attack to better understand blood clots that can form in the heart's main pumping chamber. Using special PET/MR scans, researchers tracked clot activity in the heart and brain over several months. The goal was to learn how these clots form, change, and dissolve, which could lead to better ways to prevent strokes and other complications.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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100 people
The number who actually took part.
- Started
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Jan 2020
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
100 patients following anterior myocardial infarction.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or females over the age of 40 with recent (within 21±2 days) acute type 1 anterior myocardial infarction * Provision of informed consent prior to any study specific procedures Exclusion Criteria: * Inability or unwilling to give informed consent. * Concomitant use of anticoagulation agents (warfarin, apixaban, edoxaban, rivaroxaban, dabigatran or SC/IV Heparin) (Cohort 1 only) * Unable to tolerate the supine position * Impaired renal function with eGFR of \<30 mL/min/1.73m2 * Severe or significant comorbidity * Women who are pregnant or breastfeeding • Severe claustrophobia
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Royal Infirmary Edinburgh
Edinburgh, United Kingdom
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Other studies related to the condition(s) this trial covers.
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