Sun simulator study seeks clues to skin cancer risk

NCT ID NCT06177106

Recruiting now Knowledge-focused Sponsor: University of Arizona Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study exposes small areas of sun-damaged skin to simulated sunlight to see how proteins and genes change. Researchers will compare 46 adults—half with a history of skin cancer, half without—to find differences that might explain cancer risk. Participants will have four small skin biopsies over four weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Solar Simulated Light
What this could lead to: If successful, this could help explain why some people with sun-damaged skin develop skin cancer while others do not, potentially guiding future prevention strategies.
What could go wrong: This is a small, early observational study (46 participants) that does not test a treatment. It only looks at short-term protein changes after one sun exposure, which may not reflect real-world risk.

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Conditions

The condition(s) this trial relates to.

radiation injury skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OTHER SKIN CHANGES DUE TO CHRONIC EXPOSURE TO NONIONIZING RADIATION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

University of Arizona Cancer Center
RECRUITING

Tucson, Arizona, 85719, United States

Contact

Contact Email: •••••@•••••

Contact Email: •••••@•••••

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