University Of Arizona

This early-phase trial will test whether adding semaglutide (a GLP-1 drug used for diabetes and weight loss) to standard chemotherapy is safe and tolerable for people with metastatic pancreatic, colorectal, or liver cancer. About 30 participants will receive weekly semaglutide in…

This early-phase trial tests a new approach using donor immune cells that have been mobilized through exercise to prevent or treat leukemia relapse after a stem cell transplant. The study will enroll 94 people with various blood cancers. Some will receive the exercise-mobilized c…

This study aims to make cervical cancer screening easier for people who are unhoused or unstably housed. Researchers will bring a mobile health unit to community locations in Tucson, Arizona, where participants can learn about cervical cancer, collect their own sample for HPV tes…

This study compares two vaginal treatments—estrogen and DHEA—for relieving menopause symptoms like vaginal dryness, discomfort, and painful intercourse. About 324 women aged 40-90 will use one of the treatments and report changes in symptoms and sexual health. The goal is to help…

This study tests whether using a virtual reality headset for guided muscle relaxation can help people undergoing cell therapies like CAR-T or stem cell transplant feel better. Participants will use the VR headset once daily for up to 20 minutes during their hospital stay. Researc…

This study compares two types of stitches used to close the belly muscle after a C-section: a new barbed suture (Stratafix) versus the standard smooth suture (PDS). The goal is to see if the barbed stitch leads to less pain and less need for narcotic painkillers in the first two …

This study tests whether a 5-minute guided breathing technique called box breathing can help older adults (65+) manage stress and recover better after total knee replacement. Thirty-two participants will be randomly assigned to either the breathing exercise or a control activity.…

This study tests whether adding telephone health coaching to a symptom management handbook helps reduce symptom burden and improve quality of life for people with metastatic breast, GI, or melanoma cancer and their caregivers. About 200 participants will be split into two groups:…

This study tests whether reducing blue light exposure in the evening—using amber-tinted glasses or smart lightbulbs—can help children ages 5 to 6 fall asleep faster. Sixty children with sleep difficulties will be randomly assigned to one of three light-reducing strategies for two…

This study tests whether taking N-acetylcysteine (NAC), a common supplement, before and after hand or foot surgery can reduce pain and the need for opioid painkillers. About 80 adults will be randomly assigned to take NAC or a placebo for 14 days. Researchers will track pain, fun…

This study looks at whether wearing a continuous glucose monitor (CGM) and receiving education can help teenagers with prediabetes improve their blood sugar levels and adopt healthier behaviors. Twenty-five teens aged 13-17 will take part in a 20-week program, first receiving sta…

This study tests whether green light therapy can reduce pain in people with fibromyalgia by calming brain inflammation. Researchers will use brain scans and spinal fluid tests to see how the light affects pain pathways. The trial involves 70 adults with moderate to severe pain wh…

This study tests whether transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique, can improve the brain's natural waste-clearing system (glymphatic function) in people with mild cognitive impairment. Researchers will give TMS to 20 participants to see …

This study aims to understand what causes preeclampsia, a serious pregnancy condition. Researchers will measure a protein called sFlt1 in the blood of 500 women, including those with and without the condition. The goal is to find better ways to diagnose and treat this disease in …