University Of Arizona

This study tests a combination of two drugs, atezolizumab and cabozantinib, in 30 people with advanced pancreatic cancer that has spread and stopped responding to standard treatments. The goal is to see if the combo can shrink tumors or slow the disease. Researchers will also che…

This study tests a combination of two drugs (atomoxetine and oxybutynin) given at bedtime to children with Down syndrome who have obstructive sleep apnea. The goal is to see if the treatment improves breathing during sleep and thinking skills. Thirty-six children aged 6 to 17 wil…

This study tests a nutrition program made for Beninese adults with type 2 diabetes. 64 participants will either get the tailored program or usual care. The goal is to see if the program improves blood sugar and healthy eating over 6 months, with effects lasting up to a year.

This study tests whether a time-efficient breathing exercise (inspiratory muscle strength training) can lower blood pressure and improve heart health in adults aged 50 and older with moderate to severe obstructive sleep apnea. Participants who cannot or will not use a CPAP machin…

This study tests a new software that combines MRI and ultrasound images in real time to help doctors more accurately detect and locate aggressive prostate cancer during biopsy. About 100 men scheduled for a standard prostate biopsy will take part. The goal is to improve early dia…

This study tests whether metformin, a common diabetes drug, can prevent oral cancer in 34 people with precancerous white or red patches in the mouth. Participants take metformin to see if it can reverse or stop these patches from turning into cancer. The goal is to find a safe, l…

This study tests whether a combination of two creams—calcipotriene (a form of vitamin D) and 5-fluorouracil (a chemotherapy cream)—can prevent skin cancer in organ transplant recipients. These patients have a high risk of developing skin cancer from precancerous spots called acti…

This study looks at whether trained service dogs can help military veterans with PTSD feel better over time. About 150 veterans who already qualify for a service dog will be randomly assigned to get one or wait. Researchers will track PTSD symptoms, depression, and daily life for…

This study looks at whether having a psychiatric service dog helps veterans with PTSD get more out of a standard therapy called prolonged exposure therapy. About 216 veterans who already qualify for a service dog will take part. The goal is to see if the dog-and-therapy combo red…

This study tests whether adding a second drug (dexmedetomidine) to the standard nerve block medication (dexamethasone) can make pain relief last longer after shoulder, foot, or ankle surgery. About 100 adults will receive either the combo or the standard block, then report their …

This study looks at whether putting weight on your ankle sooner after surgery for a broken ankle helps you recover faster and return to work sooner. About 150 adults with certain types of ankle fractures will be randomly assigned to start walking right away or wait several weeks.…

This study looks at whether specific voice exercises can improve voice quality in older adults whose voices have weakened with age. Researchers will measure changes in vocal cord function and how listeners rate voice quality. The goal is to understand which therapy tasks work bes…

This study tests whether using a green LED light at home for 2 hours each day can reduce chronic pain and improve quality of life. About 55 adults with conditions like fibromyalgia or nerve pain from HIV or chemotherapy will take part. The goal is to see if this safe, drug-free a…

This study tests whether a culturally adapted strength training program, done together with a caregiver, is feasible and beneficial for Hispanic prostate cancer survivors and their caregivers. The program involves remote group exercise classes over 3 months, with a 3-month follow…

This small study tests whether six weeks of special breathing exercises (called inspiratory muscle strength training) can improve heart and lung function in people with pulmonary hypertension, a condition where blood pressure in the lungs is too high. Four participants will do th…

This study tests a program to help Hispanic cancer survivors and their caregivers eat healthier and be more active. The goal is to reduce common symptoms like pain, sleep trouble, and anxiety. About 187 survivors and their caregivers will take part in this 25-week program.

This study looks at how many times a needle should be passed through a muscle during trigger point injections to best relieve myofascial pain. Researchers will randomly assign 300 adults to receive 2, 10, or 20 needle passes per trigger point. The goal is to find the minimum numb…

This study measures brain activity and chemical levels in people with epilepsy who already have electrodes implanted for medical reasons. Participants play simple computer games while their brain signals are recorded. The goal is to better understand how the brain works during th…

This study looks at how different baby formulas change the bacteria in a baby's gut. Researchers will compare standard formula, a new formula designed to be more like breast milk, and breast milk itself. About 240 healthy, full-term babies born vaginally will take part. The goal …

This study looks at how green light exposure might change the way the brain processes pain. Researchers will measure brain activity in 30 healthy adults (ages 18–50) with no chronic pain. The goal is to understand the mechanism, not to test a treatment.

This study looks at how the brain handles two different tasks: remembering daily events (like when you last took medicine) and finding your way around. Researchers will test healthy adults and epilepsy patients using virtual environments and memory games. The goal is to understan…

This study follows about 120 children who received one booster dose of the HPV vaccine (Gardasil 9) to see how long their immune protection lasts. Researchers will measure antibody levels in blood samples taken at 4, 5, and 6 years after the first vaccine dose. The goal is to und…