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Can a natural protein fragment help the brain heal after severe injury?

NCT ID NCT06282965

Recruiting now Disease control Sponsor: University of Arizona Source: ClinicalTrials.gov ↗

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial tests whether Angiotensin (1-7), a synthetic version of a natural protein fragment, is safe and effective for people with moderate to severe traumatic brain injury (TBI). Participants receive a daily injection for 21 days, along with blood tests, MRI scans, and cognitive assessments. Researchers compare two different doses of the drug against a placebo to see if it improves mental functioning and reduces physical signs of brain damage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Angiotensin (1-7), a synthetic version of a natural protein fragment, given as a daily injection
What this could lead to
If it works, this could point toward a new treatment to help people recover mental function and reduce brain damage after a traumatic brain injury.
What could go wrong
This is an early-stage trial with a small number of participants, so results may not apply broadly. The drug's safety and effectiveness are still unproven, and it may not improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

  • University of Arizona

    RECRUITING

    Tucson, Arizona, 85724, United States

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