Can a bone graft improve ACL surgery outcomes?

NCT ID NCT06975306

Recruiting now Disease control Sponsor: University of Arizona Source: ClinicalTrials.gov ↗

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This trial tests whether filling the bone gap left after ACL reconstruction with a patient's own bone or a processed bone product leads to better outcomes. Adults aged 18-40 undergoing ACL surgery with a bone-patellar tendon-bone graft will be randomly assigned to receive either an autologous bone graft or demineralized bone matrix putty. Researchers will compare pain, knee function, range of motion, and complications between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: autologous bone graft or demineralized bone matrix (DBM) putty
What this could lead to: If successful, this could identify a better way to fill the bone gap after ACL surgery, potentially reducing pain and improving knee function and recovery.
What could go wrong: This is a relatively small trial, and results may not apply to everyone. Possible risks include graft displacement, infection, or complications from the procedure.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACL INJURIES BONE GRAFT; COMPLICATIONS

Contacts and locations

Locations

Banner Health Center Plus - Arcadia
RECRUITING

Phoenix, Arizona, 85008, United States
Banner Sports Medicine Scottsdale
RECRUITING

Scottsdale, Arizona, 85256, United States
Banner University Medical Center Phoenix
RECRUITING

Phoenix, Arizona, 85006, United States

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