Personalized Omega-3s: a genetic key to heart health?

NCT ID NCT07078344

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether omega-3 supplements can reduce inflammation and improve heart health differently depending on a person's genetic makeup and ancestry. Two hundred healthy adults of African or European descent will take omega-3s or a placebo for 12 weeks each, then switch. Researchers will measure fatty acid levels and inflammation markers to see if genetic variations affect the response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Omega-3 fatty acids

What this could lead to

If successful, this could show that omega-3 supplements are more effective for certain genetic groups, paving the way for personalized heart health recommendations.

What could go wrong

This is a Phase 2 trial with only 200 participants, so results may not apply to everyone. The study focuses on biomarkers, not hard outcomes like heart attacks, so real-world benefits remain uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arizona Cancer Center

    RECRUITING

    Tucson, Arizona, 85719, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Georgetown University

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20057, United States