Personalized Omega-3s: a genetic key to heart health?

NCT ID NCT07078344

Recruiting now Disease control Sponsor: University of Arizona Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether omega-3 supplements can reduce inflammation and improve heart health differently depending on a person's genetic makeup and ancestry. Two hundred healthy adults of African or European descent will take omega-3s or a placebo for 12 weeks each, then switch. Researchers will measure fatty acid levels and inflammation markers to see if genetic variations affect the response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Omega-3 fatty acids
What this could lead to: If successful, this could show that omega-3 supplements are more effective for certain genetic groups, paving the way for personalized heart health recommendations.
What could go wrong: This is a Phase 2 trial with only 200 participants, so results may not apply to everyone. The study focuses on biomarkers, not hard outcomes like heart attacks, so real-world benefits remain uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES HEART HEALTH MARKERS OMEGA-3 FATTY ACIDS

Contacts and locations

Locations

Arizona Cancer Center
RECRUITING

Tucson, Arizona, 85719, United States
Georgetown University
NOT_YET_RECRUITING

Washington D.C., District of Columbia, 20057, United States

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