Could a type 2 diabetes drug help pregnant women control blood sugar?

NCT ID NCT05482789

Recruiting now Symptom relief Sponsor: Maisa N. Feghali, MD Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing how exenatide, a drug already used for type 2 diabetes, works in pregnant women with gestational diabetes. Researchers will measure how the body processes the drug and how well it controls blood sugar after a meal. The study involves 13 pregnant women who do not yet need medication for their gestational diabetes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Exenatide
What this could lead to: If it works, this could point toward a new treatment option for gestational diabetes when standard therapies are not suitable.
What could go wrong: This is a very small pilot study with only 13 participants, so results may not apply broadly. Exenatide is not yet approved for use in pregnancy, and its safety for the baby is unknown.

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Conditions

The condition(s) this trial relates to.

gestational diabetes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GESTATIONAL DIABETES

Contacts and locations

Locations

Magee Womens Hospital of UPMC
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States

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