Pill vs needle: major study tests better way to treat pregnancy diabetes

NCT ID NCT06445946

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 27 times

Summary

This study compares two treatments for gestational diabetes (high blood sugar during pregnancy): oral metformin pills and injectable insulin. About 1,572 pregnant women who need medication will be randomly assigned to one treatment. Researchers will track health outcomes for mothers and babies up to 2 years after birth to see if metformin works as well as insulin and is safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

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Locations

  • Austin Maternal Fetal Medicine

    NOT_YET_RECRUITING

    Austin, Texas, 78758, United States

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  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

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  • Brown University

    RECRUITING

    Providence, Rhode Island, 02912, United States

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  • Cedars Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

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  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10032, United States

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  • Eastern Virginia Medical School - Old Dominion University

    RECRUITING

    Norfolk, Virginia, 23501, United States

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  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

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  • Premier Health - Miami Valley Hospital

    RECRUITING

    Dayton, Ohio, 45409, United States

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  • The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine

    RECRUITING

    Columbus, Ohio, 43210, United States

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  • Tufts University

    RECRUITING

    Boston, Massachusetts, 02111, United States

    Contact Email: •••••@•••••

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  • University of Alabama

    RECRUITING

    Tuscaloosa, Alabama, 35487, United States

    Contact Email: •••••@•••••

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  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

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  • University of New Mexico

    RECRUITING

    Albuquerque, New Mexico, 87131, United States

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  • University of Pennsylvania

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Email: •••••@•••••

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  • University of South Carolina Greenville

    RECRUITING

    Greenville, South Carolina, 29605, United States

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  • University of South Florida

    RECRUITING

    Tampa, Florida, 33620, United States

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  • University of Texas Austin

    RECRUITING

    Austin, Texas, 78705, United States

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  • University of Texas Health Science Center

    RECRUITING

    Houston, Texas, 77030, United States

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  • Wake Forest University

    RECRUITING

    Winston-Salem, North Carolina, 27106, United States

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  • Washington University in St. Louis

    NOT_YET_RECRUITING

    St Louis, Missouri, 63130, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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