Smart supplement strategy could save babies in ethiopia

NCT ID NCT06125860

First seen Jan 05, 2026 · Last updated Jun 22, 2026 · Updated 33 times

Summary

This study in Addis Ababa, Ethiopia, tests whether giving protein supplements only to pregnant women who are undernourished can prevent problems like low birth weight and stillbirth. Over 6,700 pregnant women are randomly assigned to receive supplements either universally or only if they are underweight. Researchers will compare which strategy works best and is most cost-effective.

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Contacts and locations

Locations

  • Addis Continental Institute of Public Health (ACIPH)

    Addis Ababa, Addis Ababa, Box 26751/1000, Ethiopia

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

balanced energy and protein (BEP) dietary supplement

What this could lead to

If successful, this could show that targeting supplements to undernourished pregnant women is just as effective as giving them to everyone, saving resources and preventing complications like low birth weight.

What could go wrong

This is an effectiveness study, not a drug trial, so the supplement is already known to be safe. However, the results may not apply to other populations or settings, and the targeting strategies might not improve outcomes as hoped.

Conditions

The condition(s) this trial relates to.

Birth Weight fetal growth restriction Gestational Weight Gain Perinatal Death pregnancy disorder with abortive outcome Premature Birth Stillbirth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.