PRETERM BIRTH

This study is testing whether a single, lower dose of a steroid medicine is just as safe and effective as the standard two-dose treatment for pregnant people at risk of delivering their baby too early. The medicine helps speed up the baby's lung development before birth. Research…

This study is testing if giving weekly cash payments to low-income mothers helps them spend more time with their premature babies in the hospital's intensive care unit (NICU). Researchers want to see if this financial support reduces stress and allows mothers to provide more brea…

This study is testing whether a new combination of three antibiotics works better than the current standard antibiotics to help prolong pregnancy and improve outcomes for both mother and baby when water breaks too early (before 34 weeks). The research involves 56 hospitalized pre…

This study is testing different ways to provide nutritional supplements to pregnant women in Addis Ababa, Ethiopia, to see which method works best at preventing problems like babies being born too small, too early, or stillborn. Researchers will enroll 6,750 pregnant women and gi…

This large international study is testing whether treating hidden urine infections in pregnant women can prevent serious birth complications. Researchers are enrolling over 1,100 pregnant women in developing countries to see if antibiotics reduce preterm births, small babies, and…

This study aims to find the best way to prevent early (preterm) birth in pregnant women who have a short cervix, which is a known risk factor. It will compare two approaches: using a vaginal progesterone gel alone versus using the gel plus a cervical cerclage (a small stitch plac…

This study is testing whether a daily supplement containing probiotics and prebiotics (called synbiotics) can help prevent preterm birth in pregnant women at high risk. Researchers want to see if improving the balance of healthy bacteria in the vagina early in pregnancy can help …

This study is testing if finding and treating malaria very early in pregnancy can prevent serious problems for newborns. It will compare a new strategy—using a highly sensitive malaria test in the first three months of pregnancy—against standard prenatal care. The goal is to see …

This study is testing if a medication called sulfasalazine can help prevent pregnant women from having another preterm birth. It will involve 50 women with a history of early delivery. Researchers will check if the drug lowers a specific hormone in the blood and if it actually re…

This study is testing whether giving caffeine very early to extremely premature babies can help prevent sudden kidney injury. Researchers will compare caffeine treatment to standard supportive care in 236 newborns born before 32 weeks. The goal is to see if caffeine reduces kidne…

This study aims to understand how exposure to high temperatures during pregnancy affects the health of mothers and their babies. Researchers will follow 6,000 pregnant women in rural Pakistan, measuring their heat exposure and tracking pregnancy outcomes like birth weight and pre…

This UK study aims to understand how caring for a very premature baby affects families' wellbeing, finances, and daily life over the first year at home. It focuses on babies with and without a serious bowel condition called necrotising enterocolitis (NEC). Researchers will follow…

This study is testing if two non-invasive scanning methods can predict which premature babies will develop a serious, chronic lung disease called bronchopulmonary dysplasia (BPD). Researchers will use a special electrical scan and an ultrasound on 104 very small, premature babies…

This study aims to understand how a mother's stress and life experiences might affect tiny energy centers in her cells (mitochondria) and inflammation, potentially increasing the risk of preterm birth. Researchers will follow 180 pregnant women to see if different stress profiles…

This study aims to understand why some young adults born very prematurely don't see fitness improvements from standard aerobic exercise. Researchers will compare 60 inactive adults, some born preterm and some at term, to look for differences in their cells' energy-producing compo…

This is a long-term observational study that will follow 2800 pregnant women and their families in Weifang, China, for up to 18 years. The goal is to understand how factors like environment, nutrition, and lifestyle during pregnancy affect the short-term and long-term health of b…

This study aims to understand how different ways of presenting artificial intelligence (AI) predictions affect doctors' judgment when assessing the risk of preterm birth. Doctors specializing in pregnancy care will review simulated patient cases online, make decisions, and see ho…

This study is investigating whether immediate skin-to-skin contact between a mother and her preterm baby after birth can influence the baby's stress-related genes and improve their development. Researchers will compare 60 preterm babies who receive this immediate contact with tho…

This study aims to find the best time during a routine pregnancy ultrasound to measure cervical length, which helps predict the risk of early birth. Researchers will compare measurements taken at the beginning versus the end of the ultrasound exam in 550 pregnant participants. Th…