PRETERM BIRTH

The ROOT study is testing a personalized nutrition program for pregnant women. Participants receive standard prenatal care plus customized diet and lifestyle plans based on their genes and nutrient levels. The goal is to see if this approach can lower the chances of preterm birth…

This study tests whether portable AI-driven ultrasound devices can help frontline health workers in rural Ethiopia detect pregnancy complications early. About 1,059 pregnant women will be split into three groups: two using different AI ultrasound tools and one receiving standard …

This study tests a personalized support program called PTBCARE+ for pregnant individuals at high risk of delivering early. The program includes a stress reduction toolkit, a website/app, care coordination, and optional massage. Researchers will compare stress levels and birth out…

This study tests whether a simple, low-cost oral health program for pregnant women in rural Nepal can reduce the number of babies born too early, too small, or underweight. About 2,280 women will either receive daily antiseptic mouthwash and intensive oral hygiene education, or j…

This study will test whether screening pregnant women for chlamydia and gonorrhea can reduce the risk of preterm birth. About 2,000 women in Botswana will be randomly assigned to receive either standard care or additional STI testing early in pregnancy and again in the third trim…

This study tests a new way to prevent preterm birth by first giving pregnant women a simple risk score. Those at high risk then get a special ultrasound to check the cervix, followed by proven treatments if needed. Researchers will compare this approach to standard care in 1,000 …

This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) can help mothers of premature or sick babies in the NICU produce more breast milk. About 40 mothers will receive either the supplement or a placebo for several weeks. The goal is to see if t…

This study will test whether a culturally-based live music intervention can reduce stress and lower the risk of preterm birth in pregnant Black women. 142 women in their first trimester will be randomly assigned to either music sessions or a verbal support group. Researchers will…

This pilot study tests whether giving caffeine to preterm infants (born 28-34 weeks) who need breathing support can help them leave the hospital sooner. About 62 babies will receive either caffeine or a placebo daily while on respiratory support. The study aims to see if a larger…

This study looks at whether pregnant women at high risk of preterm birth can safely express breastmilk from week 28 to 34 of pregnancy. Researchers will check if it affects how soon the baby is born, how much milk is available at birth, and whether it helps with breastfeeding. Th…

This study looks at whether recommending bed rest to pregnant women with a short cervix actually helps prevent preterm birth. Researchers will compare women who are told to rest with those who continue normal daily activities. The goal is to see if avoiding bed rest is just as sa…

This study looks at the best amount of oxygen to give babies born between 32 and 35 weeks right after birth. Researchers will compare giving 60% oxygen versus 30% oxygen to over 1,500 babies in Alberta hospitals. The goal is to see which level helps babies breathe better and need…