PRETERM BIRTH

This study aims to see if portable ultrasound devices, guided by artificial intelligence (AI), can help frontline health workers in rural Ethiopia provide better pregnancy care. It will compare two different AI-ultrasound tools against standard care without ultrasound. The goal i…

This study aims to find the safest amount of oxygen to give to babies born 6-8 weeks early (32-35 weeks) right after birth. Researchers will compare giving 60% oxygen versus 30% oxygen to see which helps babies breathe better and need less breathing support in their first hour. T…

This study is testing whether a dietary supplement called nicotinamide riboside (NR) can help mothers of babies in the Neonatal Intensive Care Unit (NICU) produce more breast milk. It will involve 40 mothers whose babies are expected to stay in the NICU for at least four weeks. M…

This is a small pilot study to see if a larger trial is possible. It will test if giving caffeine to preterm babies (born 28-34 weeks) who need help breathing can help them get healthy enough to leave the hospital faster. Researchers will compare caffeine to a placebo (inactive s…

This study is testing whether a structured home-based program of play, sensory activities, and exploration can improve brain, motor, and thinking skills in babies born prematurely. The program is led by parents with guidance from a therapist and does not involve any medicine. Res…

This study aims to find out if routinely checking pregnant women for two common sexually transmitted infections (chlamydia and gonorrhea) and treating them can help prevent babies from being born too early (preterm birth). About 2,000 pregnant women in Botswana will be randomly a…

This study aims to see if pregnant women at high risk of early birth can safely express and store breastmilk starting at 28 weeks. Researchers want to know if having this milk ready right after birth helps feed the newborn and supports the mother's breastfeeding journey. They wil…

This study is testing if a special live music program can help reduce chronic stress in pregnant Black women, with the goal of lowering the risk of preterm birth. Researchers will compare the music program to a simple talk session. They aim to see if reducing stress through music…

This study is testing whether a special chewing gum containing xylitol can prevent early (preterm) birth and low birth weight in babies. It will involve 6,000 pregnant women in Malawi, who will chew either a higher or lower dose of xylitol gum or a placebo gum daily. The goal is …

This study is testing a new two-step method to try to prevent babies from being born too early. First, pregnant women fill out a simple checklist to see if they are at higher risk. Those with a high score get a special ultrasound to check the cervix. If the cervix is short, they …

This study is testing a personalized prenatal support program called PTBCARE+ to see if it can lower stress and reduce the risk of early delivery in pregnant people who are at high risk for having a preterm baby. Researchers will compare about 1,200 participants who receive the e…