PRETERM BIRTH

This study tests a program that gives pregnant women personalized nutrition and lifestyle advice based on their genes and nutrient levels. The goal is to see if this approach can lower the chances of problems like preterm birth, preeclampsia, and gestational diabetes. About 500 p…

This study tests a personalized support program (PTBCARE+) for pregnant individuals at high risk of delivering early. About 1,228 participants will either receive the program—which includes stress reduction tools, a website/app, and massage—or standard prenatal care. The goal is …

This study will see if testing and treating pregnant women for chlamydia and gonorrhea can lower the chance of having a baby too early (preterm birth). About 2,000 pregnant women in Botswana will be split into two groups: one gets usual care, the other gets extra STI tests early …

This study tests a new way to prevent preterm birth by first giving pregnant women a simple risk score. Those at high risk then get a special ultrasound to check the cervix, followed by proven treatments if needed. Researchers will compare this approach to standard care in 1,000 …

This study tests whether a simple, low-cost oral health program for pregnant women can reduce the number of babies born too early or too small. About 2,280 pregnant women in rural Nepal will either receive daily antiseptic mouthwash and intensive oral hygiene education, or just a…

This study will test if chewing gum containing xylitol (a natural sweetener) during pregnancy can reduce the risk of preterm birth and low birthweight. About 6,000 pregnant women in Malawi will be randomly assigned to chew one of two doses of xylitol gum or a placebo gum daily. T…

This pilot study will test whether giving caffeine to preterm babies (born 28-34 weeks) who need breathing help can shorten their stay in the Neonatal Intensive Care Unit (NICU). About 62 infants will be randomly assigned to receive either caffeine or a placebo daily while on res…

This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) can help mothers of premature or sick babies produce more breast milk while their infant is in the NICU. About 40 mothers will receive either the supplement or a placebo for several weeks. T…

This study will test whether a culturally-based live music intervention can lower stress and reduce the risk of preterm birth in pregnant Black women. Researchers will compare the music group to a control group that only receives verbal support. The goal is to see if music can im…

This study looks at whether prescribing bed rest to pregnant women with a short cervix actually helps prevent early birth. Researchers will compare women who are told to rest with those who are not, tracking how far along they are when they give birth. The goal is to see if avoid…

This study tests whether AI-assisted ultrasound devices can help frontline health workers in rural Ethiopia detect pregnancy complications early, potentially reducing deaths of mothers and newborns. About 1,059 pregnant women will be split into three groups: two using different A…

This study looks at whether a structured home-based program of sensory and motor activities can improve brain development in babies born early (before 37 weeks). About 28 preterm infants will take part, with parents guided by therapists. The study does not use any drugs or device…

This study looks at whether pregnant women at high risk of early delivery can safely express breastmilk starting at week 28. Researchers will check if this practice affects how soon the baby is born, how much milk is available at birth, and the nutritional content of the first mi…

This study looks at what amount of oxygen is safest for babies born between 32 and 35 weeks of pregnancy. Right after birth, these babies will get either 60% or 30% oxygen to see which helps them breathe better and need less breathing support after one hour. Over 1,500 babies in …