PRETERM BIRTH

This study compares two ways of fortifying breast milk for preterm babies in the NICU. One group gets standard fortification, while the other gets a personalized mix based on real-time milk analysis. Researchers will track growth, brain scans, and development up to age 2 to see w…

This study looks at the best way to control blood sugar in pregnant women with diabetes who receive steroids to help their baby's lungs develop before a possible early birth. About 120 women will be randomly assigned to one of three insulin strategies. The goal is to find which a…

This study tests a new therapy for preterm babies born before 32 weeks who show abnormal general movements, a sign of possible developmental problems like cerebral palsy. The therapy involves gently guiding the baby's stiff or cramped movements into more normal, fluid patterns. R…

This study tests whether a special food supplement with added omega-3s and choline can help undernourished pregnant women carry their babies longer and improve their babies' brain development. It also tests a simple talk therapy program to reduce depression during and after pregn…

This study compares two ways of giving breathing support (PEEP) to very premature babies right after birth. One method uses a steady pressure, the other starts high then lowers it. The goal is to see which approach reduces the chance of death or chronic lung disease. Over 900 bab…

This study planned to see if placing preterm babies in a plastic bag during kangaroo mother care (skin-to-skin contact) could prevent hypothermia. It aimed to enroll infants born at 32 to 36 weeks. However, the trial was withdrawn before any participants were enrolled, so no data…

This study in Addis Ababa, Ethiopia, tests whether giving protein supplements only to pregnant women who are undernourished can prevent problems like low birth weight and stillbirth. Over 6,700 pregnant women are randomly assigned to receive supplements either universally or only…

This study tests whether screening pregnant women for malaria with a highly sensitive rapid test during the first trimester, followed by treatment if positive, can improve newborn health. Over 2,000 women in malaria-prone areas will be compared to those receiving usual care. The …

This study looks at whether the Nurse-Family Partnership program, where nurses visit first-time, low-income mothers during pregnancy and early childhood, can prevent preterm birth, low birth weight, and injuries in children. About 6,000 mothers in South Carolina are taking part. …

This study looks at whether a structured home-based program of sensory and motor activities can improve brain, movement, and thinking skills in preterm infants. About 28 babies born before 37 weeks will take part. Parents will guide the activities with therapist support, and no m…

This study follows 90 children born very prematurely (before 32 weeks) at ages 2, 5, and 10. A team of experts checks their mental and physical health, sleep, and quality of life. Parents use an app to answer questions, and the team gives recommendations for further care. The goa…

This study tests a program called WE CARE in the NICU, which screens families of preterm babies for unmet social needs like housing or job insecurity and provides referrals to community resources. About 882 mothers and their preterm infants (born before 34 weeks) will take part. …

This study is testing whether wireless, wearable sensors can safely and accurately monitor heart rate, breathing, temperature, and oxygen levels in 75 newborn babies in the NICU. The goal is to see if these wireless devices work as well as the standard wired monitors, and if they…

This study follows children born moderately or late preterm (32-36 weeks) to age 9, measuring their thinking, movement, language, behavior, and growth. Researchers compare these kids to full-term peers to understand long-term effects. The goal is to learn how early development pr…

This study follows 9,000 pregnant women in Zambia from early pregnancy through one year after birth. Researchers collect medical details and biological samples to learn why preterm births happen, with the goal of finding new ways to prevent them. No treatment is given—this is an …

This study looks at ways to help mothers of preterm or low birth weight infants in rural India continue Kangaroo Care (skin-to-skin contact) at home after leaving the hospital. Researchers will work with 190 mothers and healthcare providers to understand what support is needed. T…

This study looks at the tiny organisms living in the vagina of women pregnant with twins to see if they are linked to preterm birth. Researchers will take swabs and blood samples from 120 women at different points in pregnancy. The goal is to find clues that could one day help pr…