Can a Nutrient-Packed supplement boost baby brain development and prevent early birth?

NCT ID NCT05949190

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special food supplement with added omega-3s and choline can help undernourished pregnant women carry their babies longer and improve their babies' brain development. It also tests a simple talk therapy program to reduce depression during and after pregnancy. About 1,660 women in Sierra Leone are taking part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Maternal Ready-to-Use Supplementary Food with DHA/EPA/choline, azithromycin, albendazole, sulfadoxine pyrimethamine, cognitive behavioral therapy, insecticide-treated mosquito net

What this could lead to

If successful, this could show that adding specific nutrients to a supplement can prolong pregnancy and improve infant brain development, and that a simple therapy can reduce depression in pregnant women.

What could go wrong

This is a large trial, but results may not apply to other populations. The supplements and therapies are generally safe, but individual responses may vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nutritional deficiency disease postpartum depression Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bandajuma

    Bandajuma, Southern Province, Sierra Leone

  • Bendu Malen

    Bendu, Southern Province, Sierra Leone

  • Blama Massaquoi

    Blama Massaquoi, Southern Province, Sierra Leone

  • Futa Peje

    Futa Peje, Southern Province, Sierra Leone

  • Gbondapi

    Gbondapi, Southern Province, Sierra Leone

  • Nyandehun Malen

    Nyandehun, Southern Province, Sierra Leone

  • Potoru

    Potoru, Southern Province, Sierra Leone

  • Pujehun Static

    Pujehun, Southern Province, Sierra Leone

  • Sahn Malen

    Sahn, Southern Province, Sierra Leone

  • Zimmi

    Zimmi, Southern Province, Sierra Leone