Could a Mother's Omega-3 supplement shield preterm Babies' lungs?

NCT ID NCT02371460

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial tests whether giving mothers a DHA-rich omega-3 supplement after delivering very preterm (before 29 weeks) could improve their babies' chances of surviving without bronchopulmonary dysplasia, a chronic lung condition. Half the mothers receive DHA capsules, and half receive a placebo, taken three times daily until the baby reaches 36 weeks post-menstrual age. The goal is to see if DHA in breast milk can reduce lung damage and improve outcomes for these fragile infants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
DHA-rich algal oil (an omega-3 supplement)
What this could lead to
If it works, this could offer a simple way to improve lung health and survival in very preterm infants.
What could go wrong
This is an early-stage test, and results may not confirm a benefit. The supplement is generally safe, but its effect on severe lung disease remains uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

  • CHU de Québec-Université Laval, Centre Mère Enfant Soleil du CHUL

    Québec, Quebec, G1V 4G2, Canada

  • Centre Hospitalier Universitaire de Sherbrooke

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Children's Hospital of Eastern Ontario

    Ottawa, Ontario, K1H 8L1, Canada

  • Children's and Women's Health Centre of British Columbia

    Vancouver, British Columbia, V6H 3V4, Canada

  • Foothills Medical Centre

    Calgary, Alberta, T2N 2T9, Canada

  • Health Sciences Centre

    Winnipeg, Manitoba, R3A 1R9, Canada

  • IWK Health Centre

    Halifax, Nova Scotia, B3K 6R8, Canada

  • Jewish General Centre

    Montreal, Quebec, H3T 1E2, Canada

  • Kingston Health Science Centre

    Kingston, Ontario, K7L 2V7, Canada

  • McGill University Health Center, Glen Site, Montreal Children's Hospital

    Montreal, Quebec, H4A 3J1, Canada

  • Royal Alexander Hospital

    Edmonton, Alberta, T5H 3V9, Canada

  • Royal Columbian Hospital

    New Westminster, British Columbia, V3L 3W7, Canada

  • Royal University Hospital

    Saskatoon, Saskatchewan, S7N 0W8, Canada

  • St Boniface General Hospital

    Winnipeg, Manitoba, R2H 2A6, Canada

  • Victoria General Hospital

    Victoria, British Columbia, V8R 1J8, Canada

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