BRONCHOPULMONARY DYSPLASIA

This study aims to find the best oxygen level for premature babies who have developed a severe chronic lung disease (bronchopulmonary dysplasia) and high blood pressure in their lungs (pulmonary hypertension). Doctors will test two different oxygen level targets in 39 infants to …

This study is testing the safety of an inhaled steroid called ciclesonide in very premature babies who are at high risk for developing a serious lung condition called bronchopulmonary dysplasia (BPD). The researchers want to see if this medicine, which is already used for asthma …

This study tests whether a newer breathing support technology helps extremely premature babies breathe successfully on their own after coming off a ventilator. Researchers are comparing two non-invasive breathing support methods in babies born between 23 and 28 weeks of pregnancy…

This study is testing whether giving intravenous immunoglobulin (IVIG), a solution of antibodies, can help treat a serious lung condition called bronchopulmonary dysplasia in very premature babies. It will involve about 20 infants born between 25 and 30 weeks of pregnancy who sho…

This study is testing if an investigational drug called Zelpultide Alfa can prevent a serious lung condition called bronchopulmonary dysplasia (BPD) in extremely premature babies. The trial will enroll 366 babies born very early (between 22 and 28 weeks) who are on a breathing ma…

This study is testing whether an investigational drug called OHB-607 can prevent a serious lung condition called bronchopulmonary dysplasia (BPD) in extremely premature infants. It will compare the drug to standard neonatal care alone in about 338 babies born between 23 and 28 we…

This study aims to better understand how lungs grow and develop in premature babies, especially those with a breathing disorder called BPD. Researchers will use MRI scans (up to three times) on 160 babies in the NICU to take detailed pictures of their lungs and airways. The goal …

This study is testing a new, radiation-free imaging system called EIT to see how well it can show lung function in people with breathing problems. Researchers will use it on children and adults with conditions like chronic lung disease or muscle weakness, as well as healthy volun…

This study is testing a special pressure-sensing mattress to see if it can accurately monitor breathing and heart rate in premature babies who need breathing machine support. Researchers will enroll 60 babies in the neonatal intensive care unit to compare the mattress sensor read…

This study aims to understand how doctors decide when to remove breathing tubes from extremely premature babies and why some babies need the tube put back in. Researchers will observe 100 babies born before 28 weeks and record doctors' daily decisions about breathing support duri…

This study is testing a new, non-invasive device that measures lung function in sleeping infants. Researchers want to understand breathing patterns in premature babies with bronchopulmonary dysplasia (BPD), a chronic lung condition. The study involves 80 infants and aims to gathe…