Can the right oxygen dose save tiny lungs? new trial hopes to find out

NCT ID NCT06373289

Recruiting now Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether different oxygen targets (higher vs. lower) improve outcomes in 39 preterm infants with bronchopulmonary dysplasia and pulmonary hypertension. Each infant will experience both oxygen levels in a crossover design. The goal is to see which level reduces dangerous drops in oxygen and improves heart-lung function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oxygen therapy via pulse oximetry sensors
What this could lead to: If it works, this could help doctors choose the best oxygen levels to reduce dangerous low-oxygen events and improve survival in these fragile infants.
What could go wrong: This is a small, early crossover study (39 infants) looking at short-term oxygen events, not long-term survival. Results may not apply to all infants or change standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bronchopulmonary dysplasia pulmonary hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHOPULMONARY DYSPLASIA PULMONARY HYPERTENSION

Contacts and locations

Locations

The University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States
Yale New Haven Hospital
RECRUITING

New Haven, Connecticut, 06510, United States

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