Can the right oxygen dose save tiny lungs? new trial hopes to find out

NCT ID NCT06373289

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether different oxygen targets (higher vs. lower) improve outcomes in 39 preterm infants with bronchopulmonary dysplasia and pulmonary hypertension. Each infant will experience both oxygen levels in a crossover design. The goal is to see which level reduces dangerous drops in oxygen and improves heart-lung function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxygen therapy via pulse oximetry sensors

What this could lead to

If it works, this could help doctors choose the best oxygen levels to reduce dangerous low-oxygen events and improve survival in these fragile infants.

What could go wrong

This is a small, early crossover study (39 infants) looking at short-term oxygen events, not long-term survival. Results may not apply to all infants or change standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bronchopulmonary dysplasia pulmonary hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale New Haven Hospital

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••