Human milk mouth care may shield preemies from lung infections

NCT ID NCT06000761

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study investigates whether cleaning the mouths of very low birth weight premature infants with human milk several times a day can reduce harmful bacteria and lower the risk of lung complications like pneumonia and bronchopulmonary dysplasia. Researchers will follow 168 babies born at 30 weeks or less and weighing under 1500 grams for their first four weeks of life. The goal is to see if this simple, standardized oral care routine improves health outcomes in the neonatal intensive care unit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
human milk
What this could lead to
If effective, this simple oral care routine could reduce serious lung complications like pneumonia and bronchopulmonary dysplasia in premature infants.
What could go wrong
This is an early-stage study with a moderate number of infants, so results may not be definitive. The benefits seen in adults may not translate to newborns.

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Conditions

The condition(s) this trial relates to.

bronchopulmonary dysplasia Pneumonia, Ventilator-Associated Respiration Disorders respiratory system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Neonatal intensive care unit at Shands children's hospital at the Univeristy of Florida

    RECRUITING

    Gainesville, Florida, 32504, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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