Can scans and scope tests unlock better care for tiny lungs?

NCT ID NCT06475976

Recruiting now Knowledge-focused Sponsor: Children's Hospital of Philadelphia Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This study aims to create a new classification system for the most severe form of bronchopulmonary dysplasia (BPD), a chronic lung disease in premature infants. Researchers will use chest CT scans and bronchoscopy to gather detailed information about the lungs and blood vessels of 130 infants who need a breathing machine. The goal is to identify distinct subtypes of severe BPD and see how they relate to the child's breathing and brain development up to age two.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to better diagnosis and personalized treatment for infants with severe bronchopulmonary dysplasia.
What could go wrong: This is an observational study, not a treatment trial, so it will not directly improve outcomes. The classification system may not prove useful in practice.

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Conditions

The condition(s) this trial relates to.

bronchopulmonary dysplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHOPULMONARY DYSPLASIA

Contacts and locations

Locations

Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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