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Which inhaler works best for preterm children with lung disease? a study seeks answers

NCT ID NCT06110481

Completed Knowledge-focused Sponsor: Charles University, Czech Republic Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study looks at how children born preterm with chronic lung disease respond to different inhaled bronchodilators. Participants will have their lung function tested before and after using three types of inhalers: salbutamol, ipratropium bromide, and a combination of fenoterol with ipratropium bromide. The goal is to see if one drug or combination works better overall, and whether individual children respond differently to each treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
inhaled bronchodilators (salbutamol, ipratropium bromide, and a combination of fenoterol with ipratropium bromide)
What this could lead to
If successful, this study could help doctors choose the most effective bronchodilator or combination for children born preterm with chronic lung disease, improving their breathing treatment.
What could go wrong
This is an observational study with a small number of participants, so results may not apply to all children. Individual responses to the drugs may vary, and the study does not test long-term outcomes.

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Conditions

The condition(s) this trial relates to.

Bronchial Hyperreactivity bronchopulmonary dysplasia obstructive lung disease reactive airway disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIAL HYPERREACTIVITY BRONCHIAL OBSTRUCTION BRONCHOPULMONARY DYSPLASIA CHRONIC LUNG DISEASE OF NEWBORN CHRONIC LUNG DISEASE OF PREMATURITY PRETERM BIRTH COMPLICATION REVERSIBLE DILATATION

Contacts and locations

Locations

  • First faculty of Medicine, Charles university.

    Prague, 128 00, Czechia

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