Feeding tube placement may improve breathing in preterm babies

NCT ID NCT05777512

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study tests whether feeding preterm infants with chronic lung disease through a tube placed past the stomach (into the small intestine) helps their breathing more than feeding through a tube in the stomach. About 50 high-risk preterm babies born before 32 weeks will receive both feeding methods in a random order. Researchers will measure breathing severity and look for signs of stomach contents in the lungs to see which method is better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Jejunal (postpyloric) feeding versus gastric (nasogastric) feeding
What this could lead to
If one feeding method proves better, it could become the standard way to feed preterm infants with chronic lung disease, potentially improving their breathing and reducing complications.
What could go wrong
This is a small, early-stage trial with only 50 infants, so results may not apply to all preterm babies. The feeding tubes can cause discomfort or minor complications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

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