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Tiny lungs, big Tune-Up: can adjusting ventilator pressure help preterm babies?

NCT ID NCT06512935

Recruiting now Knowledge-focused Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how changing the pressure on a ventilator affects the lungs and heart of very premature babies (born before 34 weeks). Researchers will try different pressure levels and use ultrasound and imaging to see which setting works best for breathing and blood flow. The goal is to find a way to personalize ventilator care for these fragile infants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ventilator pressure adjustment (PEEP changes)

What this could lead to

If successful, this could help doctors set ventilators more precisely for preterm babies, potentially improving breathing and heart function.

What could go wrong

This is a very small, early study (24 infants) focused on measuring responses, not on long-term outcomes. Results may not apply to all preterm infants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adult acute respiratory distress syndrome bronchopulmonary dysplasia Hypoxia pulmonary hypertension owing to lung disease and/or hypoxia respiratory distress syndrome in premature infants

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHOPULMONARY DYSPLASIA EXTREME PREMATURITY PULMONARY HYPERTENSION DUE TO LUNG DISEASES AND HYPOXIA VENTILATION PERFUSION MISMATCH VENTILATOR LUNG; NEWBORN

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Univerisity of Alabama

    RECRUITING

    Birmingham, Alabama, 35233, United States