Feeding into the small intestine may reduce reflux and oxygen dips in fragile preterm infants
NCT ID NCT06534359
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This pilot trial tests whether feeding directly into the small intestine (transpyloric) is better than feeding into the stomach (gastric) for very preterm infants with bronchopulmonary dysplasia, a chronic lung condition. The study will measure how often babies have low oxygen levels and serious side effects, and whether the feeding method reduces acid reflux. Sixty infants born before 32 weeks will be randomly assigned to one of the two feeding methods for two weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transpyloric tube feeding (feeding into the small intestine) and gastric tube feeding (feeding into the stomach)
What this could lead to
If transpyloric feeding works better, it could offer a safer way to feed very preterm infants with lung disease, reducing reflux and dangerous drops in oxygen levels.
What could go wrong
This is a small pilot study with only 60 infants, so results may not apply to all babies. The feeding tube into the small intestine may cause its own complications, and the trial is not designed to prove long-term benefits.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Hospital Colorado
RECRUITINGDenver, Colorado, 80218, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Children's Mercy Hospital
NOT_YET_RECRUITINGKansas City, Missouri, 64108, United States
Contact Phone: •••-•••-••••
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Stanford University
RECRUITINGPalo Alto, California, 94304, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••