GASTROESOPHAGEAL REFLUX

This study tests a new, office-based method to detect Barrett's esophagus—a condition that can lead to esophageal cancer—in people who do not have chronic heartburn. Participants will answer a questionnaire, swallow a capsule balloon test (EsoCheck), and have a lab analysis (EsoG…

This study tests two common treatments for reflux in babies under 1 year old: a cow-milk-protein-free diet and the medication omeprazole. Researchers want to see which approach reduces reflux episodes better and with fewer side effects. About 96 infants will participate, and pare…

This program gives domperidone to 20 teens aged 12-21 who have severe stomach or reflux symptoms that didn't get better with standard treatments. The goal is to see if the drug can reduce their symptoms. It is a compassionate-use program, meaning it provides access to a treatment…

This study tests if wearing a special band around the outside of the throat can reduce nighttime symptoms of acid reflux, like coughing, choking, or a lump in the throat. Researchers will enroll 350 adults with GERD and track how their symptoms change. The goal is to find a simpl…

This study looks at whether hydrotalcite (Talcid) can relieve acid-related symptoms like heartburn that occur after stopping long-term use of proton pump inhibitors (PPIs). About 167 adults in Germany who have stopped taking PPIs and are experiencing rebound symptoms will take hy…

This study looks at whether a special probe can predict who will develop acid reflux after a common weight-loss surgery called sleeve gastrectomy. Researchers will follow 200 adults to see if the probe's measurements can identify those at risk. The goal is to help doctors prevent…

This study looks at how often people who take proton pump inhibitors (PPIs) for acid reflux develop a condition called small intestinal bacterial overgrowth (SIBO). Researchers will use breath tests and symptom questionnaires to measure this in 50 adults. The goal is to better un…