Simple balloon test could catch hidden esophagus cancer risk

NCT ID NCT06687603

Recruiting now Diagnosis Sponsor: Case Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study aims to see if a new office-based test (EsoCheck balloon and EsoGuard lab test) can accurately detect Barrett's esophagus in people who do not have chronic heartburn. Barrett's esophagus is a condition that can lead to esophageal cancer, but it is often missed in people without typical reflux symptoms. About 800 adults scheduled for a routine colonoscopy will take a questionnaire, swallow the capsule balloon, and then have a standard upper endoscopy to compare results.

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Conditions

The condition(s) this trial relates to.

Adenocarcinoma Of Esophagus Barrett esophagus esophageal adenocarcinoma gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BARRETT ESOPHAGUS ESOPHAGEAL ADENOCARCINOMA GASTROESOPHAGEAL REFLUX

Contacts and locations

Locations

Cleveland Clinic Taussig Cancer Center
RECRUITING

Cleveland, Ohio, 44195, United States
Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21287, United States
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44016, United States
University of Colorado
RECRUITING

Aurora, Colorado, 80045, United States
University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 027599, United States

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