GASTROESOPHAGEAL REFLUX
Clinical trials for GASTROESOPHAGEAL REFLUX explained in plain language.
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Magnetic ring for heartburn tracked for 10 years
Disease control OngoingThis registry follows 500 adults who receive the LINX device, a ring of magnetic beads implanted around the esophagus to help keep stomach acid down. The goal is to check for safety issues like device movement, erosion, or swallowing problems over up to 10 years. Participants wil…
Matched conditions: GASTROESOPHAGEAL REFLUX
Sponsor: Ethicon Endo-Surgery • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Could a prebiotic syrup help tame stubborn heartburn?
Symptom relief OngoingThis Phase 2 trial tests whether a prebiotic syrup called MHS-1031 (PIMO) can increase heartburn-free days when added to standard proton pump inhibitor (PPI) therapy for people with GERD. About 247 adults who still have heartburn despite taking PPIs will receive either the syrup …
Matched conditions: GASTROESOPHAGEAL REFLUX
Phase: PHASE2 • Sponsor: Microbiome Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Diet over pills: new study tests food as reflux remedy
Symptom relief OngoingThis study tests whether the Gracie Diet can reduce symptoms of gastroesophageal reflux disease (GERD) in adults who want to stop taking standard acid-reducing drugs. About 30 participants will stop their medication and follow the diet for 8 weeks. Researchers will track symptom …
Matched conditions: GASTROESOPHAGEAL REFLUX
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Can a simple DNA test predict esophageal cancer before it starts?
Knowledge-focused OngoingThis study aims to find early DNA changes in blood and esophageal tissue that could signal a higher risk of developing esophageal cancer. Researchers are studying 600 people with gastroesophageal reflux, Barrett's esophagus, or esophageal cancer who are already scheduled for an u…
Matched conditions: GASTROESOPHAGEAL REFLUX
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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500 obese adults donate samples to unlock secrets of weight loss
Knowledge-focused OngoingThis study collects blood, urine, and tissue samples from 500 obese adults to help researchers understand why people gain weight, lose weight, or regain weight after treatment. Participants must be over 18 with a BMI of 30 or higher. The samples will be stored for up to 10 years …
Matched conditions: GASTROESOPHAGEAL REFLUX
Sponsor: Pichamol Jirapinyo, MD, MPH • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Throat reflux study withdrawn before enrolling any patients
Knowledge-focused TerminatedThis study aimed to develop better diagnostic tests and a device (external pressure on the throat) for patients with pharyngeal reflux, where stomach contents reach the throat. It planned to include adults with GERD and throat symptoms. However, the study was withdrawn before enr…
Matched conditions: GASTROESOPHAGEAL REFLUX
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC