Tailored milk boosts preemie brain growth?

NCT ID NCT03977259

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study compares two ways of fortifying breast milk for preterm babies in the NICU. One group gets standard fortification, while the other gets a personalized mix based on real-time milk analysis. Researchers will track growth, brain scans, and development up to age 2 to see which method works better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

individualized human milk fortification with added protein and medium-chain triglycerides

What this could lead to

If successful, this approach could help preterm infants grow better and have healthier brain development, potentially reducing long-term developmental issues.

What could go wrong

This is a relatively small, early-stage study (130 infants) at a single hospital, so results may not apply broadly. The intervention is complex and may not show clear benefits over standard care.

Conditions

The condition(s) this trial relates to.

Breast Milk Expression Infant Nutrition Disorders Neurodevelopmental Disorders Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.