Tailored milk boosts preemie brain growth?

NCT ID NCT03977259

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways of fortifying breast milk for preterm babies in the NICU. One group gets standard fortification, while the other gets a personalized mix based on real-time milk analysis. Researchers will track growth, brain scans, and development up to age 2 to see which method works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
individualized human milk fortification with added protein and medium-chain triglycerides
What this could lead to
If successful, this approach could help preterm infants grow better and have healthier brain development, potentially reducing long-term developmental issues.
What could go wrong
This is a relatively small, early-stage study (130 infants) at a single hospital, so results may not apply broadly. The intervention is complex and may not show clear benefits over standard care.

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Conditions

The condition(s) this trial relates to.

Breast Milk Expression Infant Nutrition Disorders neurodevelopmental disorder nutritional disorder Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

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