Preterm birth linked to exercise resistance: mitochondrial clues emerge

NCT ID NCT06334107

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at why young adults born very preterm often don't get fitter from aerobic exercise. Researchers will compare mitochondrial DNA and fitness changes between 60 preterm-born and full-term adults after a 4-5 day per week exercise program. The goal is to find mitochondrial markers that explain this poor trainability and higher disease risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Exercise
What this could lead to
If successful, this could identify mitochondrial DNA markers that explain poor exercise response in preterm-born adults, paving the way for future targeted therapies.
What could go wrong
This is an early observational study with only 60 participants, so findings may not apply broadly. It aims to understand mechanisms, not test a treatment.

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Conditions

The condition(s) this trial relates to.

Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Texas Tech University | Kinesiology and Sport Management Building

    RECRUITING

    Lubbock, Texas, 79409, United States

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