Stitch and hormone combo may stop preterm birth
NCT ID NCT06463652
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares two approaches to prevent preterm birth in pregnant women with a short cervix: a cervical stitch (cerclage) plus vaginal progesterone versus progesterone alone. About 328 women with a singleton pregnancy and a cervix shorter than 25 mm will be randomly assigned to one of the two groups. The main goal is to see which method delays delivery longer and improves newborn health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
vaginal progesterone (Cyclogest 200 mg)
What this could lead to
If successful, this could establish a more effective way to prevent preterm birth in women with a short cervix, reducing risks for both mother and baby.
What could go wrong
This is a single-center trial, so results may not apply to all populations. The procedure (cerclage) carries risks like infection or membrane rupture, and the benefit over progesterone alone is not yet proven.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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My Duc Hospital
RECRUITINGHo Chi Minh City, Ho Chi Minh City, 70000, Vietnam
Contact Phone: •••-•••-•••• Email: •••••@•••••