Do Pre-Pregnancy Weight-Loss drugs change pregnancy outcomes?

NCT ID NCT07743567

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This study looks at whether taking GLP-1 weight-loss medications before pregnancy influences how much weight a woman gains during pregnancy and her pregnancy outcomes. Researchers will compare pregnant women who used these medications before conception with those who did not. Participants will fill out questionnaires during and after pregnancy about their medication history and feelings around food. The goal is to gather information that could help guide future recommendations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
GLP-1 receptor agonist (GLP-1RA) medications used for weight loss before pregnancy
What this could lead to
If this study finds a link, it could help doctors guide women on using GLP-1 weight-loss medications before pregnancy, potentially improving maternal and infant health.
What could go wrong
This is an observational study, so it can't prove cause and effect. Other factors may explain any differences seen, and the results may not apply to all women.

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Conditions

The condition(s) this trial relates to.

Gestational Weight Gain Obesity obesity disorder Overweight Pregnancy in Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Kansas Medical Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

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