Tiny nerves may explain endometriosis pain – study hints at smarter surgery

NCT ID NCT06286371

Completed Knowledge-focused Sponsor: Uludag University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at tissue samples from 15 women with deep endometriosis who had laparoscopic surgery. Researchers measured nerve and blood vessel density in the peritoneum near endometriosis nodules and checked pain scores before and after surgery. The goal was to see if these changes relate to pain and help determine the best surgical margin for removal. No new treatment was tested; the study aims to improve future surgical planning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help surgeons know how much tissue to remove during endometriosis surgery to reduce pain more effectively.
What could go wrong: This is a very small, completed observational study (15 people). It does not test a new treatment, so any surgical guidance is still theoretical.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometriosis endometriosis of pelvic peritoneum Pelvic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEEP ENDOMETRIOSIS ENDOMETRIOSIS ENDOMETRIOSIS-RELATED PAIN ENDOMETRIOSIS; PERITONEUM

Tiny nerves may explain endometriosis pain – study hints at smarter surgery

Summary

What this could mean

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Conditions

As listed by the trial registrant

Contacts and locations

Locations

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