Immunotherapy shows promise in extending control of resistant ovarian cancer

NCT ID NCT03430700

First seen May 20, 2026 ยท Last updated May 20, 2026

Summary

This study tested whether the immunotherapy drug pembrolizumab could help keep ovarian cancer from growing after initial chemotherapy. Twenty women with platinum-resistant ovarian, fallopian tube, or peritoneal cancer received weekly paclitaxel followed by pembrolizumab as maintenance therapy. The goal was to see if more than 16 out of 20 participants remained cancer-free for at least 6 months. The trial also studied how the immune system changes during treatment.

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Contacts and locations

Locations

  • Barts

    London, United Kingdom

  • Churchill Hospital

    Oxford, United Kingdom

  • Imperial

    London, United Kingdom

  • UCLH

    London, United Kingdom

Conditions

Explore the condition pages connected to this study.