Experimental DNA vaccine targets HPV to fight precancerous cervical cells
NCT ID NCT06276101
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested a DNA vaccine called NWRD08 in 9 women with high-grade cervical lesions caused by HPV types 16 or 18. The vaccine was given as a shot followed by a mild electrical pulse to help cells take it up. The main goal was to check safety and see if the vaccine triggers an immune response against the virus.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NWRD08 (DNA plasmid vaccine targeting HPV-16 and HPV-18)
What this could lead to
If successful, this could point toward a treatment that clears HPV infection and prevents cervical lesions from becoming cancer.
What could go wrong
This is a very early Phase 1 trial with only 9 participants, so safety and immune response are the main focus—not yet proof of effectiveness. The vaccine may not produce strong enough immunity or may cause side effects.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, 100730, China